Protein: ENSP00000405562
Gene: POM121

LinkedOmicsKB © 2022-2023 Zhang Lab

POM121:
POM121 transmembrane nucleoporin

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S81RGSRPLSSFVRKARH18------8-------------
S108HRRTLFASPLAKSTA4817-------542522--153----
S179PRSPPPRSPPPRSPP5315------63---252346456214--325
S184PRSPPPRSPPPSPPT1036517-282011773-118302834326284397
S188PPRSPPPSPPTHRAH1064574-54101672-613654493937671737133816
S345NKRRRHDSSGSGHSA7196--3316--9-13615131312--3010233
S346KRRRHDSSGSGHSAF7184--5037--9-53552121--92125
S348RRHDSSGSGHSAFEP7400--1212--45-543254494342--2512182
S351DSSGSGHSAFEPLVA6163--5340--9---151399--5172
S391HLNKRSRSSSMSSLT236------19-----------134
Showing 1 to 10 of 22 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S81RGSRPLSSFVRKARH-----------
S108HRRTLFASPLAKSTA1.6e-8-----1.6e-8----
S179PRSPPPRSPPPRSPP0.43------0.570.220.47--
S184PRSPPPRSPPPSPPT-0.34--0.91----0.0180.4---
S188PPRSPPPSPPTHRAH9.3e-4----5.1e-43.7e-43.0e-60.14-0.069-1.1e-3
S345NKRRRHDSSGSGHSA-1.8e-3--4.2e-4-------0.38-
S346KRRRHDSSGSGHSAF-0.54--3.2e-5----0.001---
S348RRHDSSGSGHSAFEP0.066-----0.118e-72.3e-3--6.9e-3-
S351DSSGSGHSAFEPLVA-0.4--0.4--------
S391HLNKRSRSSSMSSLT-----------
Showing 1 to 10 of 22 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationCCRCCS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationCOADS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationGBMS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationHNSCCS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationLSCCS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationLUADS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationOVS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationPDACS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylationUCECS81S108S179S184S188S345S346S348S351S391S393S395S396T565T569T576S584T708S714S715S722T733proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.