DLG1: discs large MAGUK scaffold protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1pdr chain A
2m3m chain A
2oqs chain A
2x7z chain A
3lra chain A
3rl7 chain A
3rl7 chain B
3rl7 chain C
3rl7 chain D
3rl7 chain E
3rl7 chain F
3rl8 chain A
3rl8 chain B
3rl8 chain C
3rl8 chain D
3rl8 chain E
3w9y chain A
4amh chain A
4amh chain B
4g69 chain A
7pc3 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T81 EPIQPVNT WEISSLP 2 42 - - - - - - - - - - 20 17 - - - - 3 2 - - S86 VNTWEISS LPSSTVT 2 17 - - - - 4 5 - - - - - - - - 6 2 - - - - S89 WEISSLPS STVTSET 1 9 - - - - - - - - - - - - - - - - - - 7 2 S90 EISSLPSS TVTSETL 3 55 - - 15 15 - - - - 12 7 - - - - - - - - 6 - T91 ISSLPSST VTSETLP 1 8 - - 8 - - - - - - - - - - - - - - - - - T93 SLPSSTVT SETLPSS 1 9 - - - - - - - - - - - - - - - - - - - 9 S94 LPSSTVTS ETLPSSL 2 33 - - - - 18 9 - - - - - - - - - - 5 1 - - T96 SSTVTSET LPSSLSP 3 83 - - 22 20 - - - - 5 2 - - 18 16 - - - - - - S99 VTSETLPS SLSPSVE 4 71 - - 4 4 - - 18 - - - - - 19 16 - - 7 3 - - S100 TSETLPSS LSPSVEK 8 178 - - 9 6 12 15 18 - - - 5 4 8 9 6 2 54 23 5 2
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T81 EPIQPVNT WEISSLP -0.36 - - - - - -0.36 - - - - S86 VNTWEISS LPSSTVT - - - - - - - - - - - S89 WEISSLPS STVTSET - - - - - - - - - - - S90 EISSLPSS TVTSETL - - - - - - - - - - - T91 ISSLPSST VTSETLP - - - - - - - - - - - T93 SLPSSTVT SETLPSS - - - - - - - - - - - S94 LPSSTVTS ETLPSSL - - - - - - - - - - - T96 SSTVTSET LPSSLSP 0.27 - 0.27 - - - - - - - - S99 VTSETLPS SLSPSVE - - - - - - - - - - - S100 TSETLPSS LSPSVEK -1.2e-3 - - - - - - - - -1.2e-3 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
T81
S86
S89
S90
T91
T93
S94
T96
S99
S100
S102
S104
Y110
T115
S122
S138
S143
S155
S158
T204
S206
T216
S232
Y399
S423
S432
S443
S517
S567
S568
S570
S571
S573
S575
T578
S579
S598
S619
T630
S635
S684
S687
S689
Y760
S765
S834
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation CCRCC T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation COAD T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation GBM T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation HNSCC T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation LSCC T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation LUAD T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation OV T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation PDAC T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation UCEC T81 S86 S89 S90 T91 S94 T96 S99 S100 S102 S104 Y110 T115 S122 S138 S143 S155 S158 T204 S206 T216 S232 Y399 S423 S432 S443 S517 S567 S568 S570 S571 S573 S575 T578 S579 S598 S619 T630 S635 S684 S687 S689 Y760 S765 S834 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T81
S86
S89
S90
T91
T93
S94
T96
S99
S100
S102
S104
Y110
T115
S122
S138
S143
S155
S158
T204
S206
T216
S232
Y399
S423
S432
S443
S517
S567
S568
S570
S571
S573
S575
T578
S579
S598
S619
T630
S635
S684
S687
S689
Y760
S765
S834
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T81
S86
S89
S90
T91
T93
S94
T96
S99
S100
S102
S104
Y110
T115
S122
S138
S143
S155
S158
T204
S206
T216
S232
Y399
S423
S432
S443
S517
S567
S568
S570
S571
S573
S575
T578
S579
S598
S619
T630
S635
S684
S687
S689
Y760
S765
S834
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.