OBSCN: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1v1c chain A
2cr6 chain A
2dku chain A
2dm7 chain A
2e7b chain A
2edf chain A
2edh chain A
2edl chain A
2edq chain A
2edr chain A
2edt chain A
2edw chain A
2eny chain A
2eo1 chain A
2gqh chain A
2mwc chain A
2n56 chain A
2yz8 chain A
4c4k chain O
4rsv chain A
4uow chain 0
4uow chain 2
4uow chain 4
4uow chain 6
4uow chain 8
4uow chain A
4uow chain C
4uow chain E
4uow chain G
4uow chain I
4uow chain K
4uow chain M
4uow chain O
4uow chain Q
4uow chain S
4uow chain U
4uow chain W
4uow chain Y
5tzm chain A
6mg9 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S136 FRCRVGGS PRPAVSW 3 181 - - - - - - - - 103 60 5 4 - - 7 2 - - - - S238 RAEGAPAS PPSTGTR 3 173 - - - - - - - - 88 49 15 12 - - 7 2 - - - - T351 VREKESAT FLCEVPQ 1 10 - - - - - - - - 6 4 - - - - - - - - - - S395 RLTVRNVS ADDDAVY 1 63 - - - - - - - - 38 25 - - - - - - - - - - T406 DAVYICET PEGSRTV 1 20 - - - - - - - - 12 8 - - - - - - - - - - S790 GRIAYQLS VQGLARF 2 90 - - - - - - - - 51 30 - - - - 7 2 - - - - S1430 EAGGQRLS FSLDVAE 1 8 - - - - - - - - - - - - - - 7 1 - - - - S1483 YKDGKKLS FSSKVRM 1 36 - - - - - - - - 21 15 - - - - - - - - - - S2326 QVRWFKGS QELQPGP 1 92 - - - - - - - - 58 34 - - - - - - - - - - S2509 YKDDTPLS PSEKFKM 1 116 - - - - - - - - 75 41 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S136 FRCRVGGS PRPAVSW -0.017 - - - - -0.017 - - - - - S238 RAEGAPAS PPSTGTR -8.5e-3 - - - - -8.4e-3 - - - - - T351 VREKESAT FLCEVPQ - - - - - - - - - - - S395 RLTVRNVS ADDDAVY -3.7e-3 - - - - -3.7e-3 - - - - - T406 DAVYICET PEGSRTV - - - - - - - - - - - S790 GRIAYQLS VQGLARF -7.6e-5 - - - - -7.6e-5 - - - - - S1430 EAGGQRLS FSLDVAE - - - - - - - - - - - S1483 YKDGKKLS FSSKVRM -8.1e-3 - - - - -8.1e-3 - - - - - S2326 QVRWFKGS QELQPGP -0.14 - - - - -0.14 - - - - - S2509 YKDDTPLS PSEKFKM -0.086 - - - - -0.086 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S136
S238
T351
S395
T406
S790
S1430
S1483
S2326
S2509
T2613
S2905
T2906
S2908
S3029
S3073
T3075
Y3077
S3373
S4015
S4076
S4092
T4136
T4148
S4151
S4750
T4754
S4757
S4783
S4804
S4805
T4813
T4828
S4829
S4871
S4989
S4991
S4993
S5022
S5034
T5254
S5526
S5563
S5567
T5569
S5571
S5573
S5669
S5938
S5955
S6201
S6773
S6808
S6812
T6815
S6817
S6829
S6831
S6851
S6881
S6942
S7023
S7075
S7091
S7116
S7178
S7218
S7220
S7232
S7244
S7264
S7265
S7450
S7454
S7654
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation CCRCC S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation COAD S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation GBM S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation HNSCC S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation LSCC S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation LUAD S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation OV S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation PDAC S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation UCEC S136 S238 T351 S395 T406 S790 S1430 S1483 S2326 S2509 T2613 S2905 T2906 S2908 S3029 S3073 T3075 Y3077 S3373 S4015 S4076 S4092 S4750 T4754 S4757 S4783 S4804 S4805 T4813 T4828 S4829 S4871 S4989 S4991 S4993 S5022 S5034 T5254 S5526 S5563 S5567 T5569 S5571 S5573 S5669 S5938 S5955 S6201 S6773 S6808 S6812 T6815 S6817 S6829 S6831 S6851 S6881 S6942 S7023 S7075 S7091 S7116 S7178 S7218 S7220 S7232 S7244 S7264 S7265 S7450 S7454 S7654 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S136
S238
T351
S395
T406
S790
S1430
S1483
S2326
S2509
T2613
S2905
T2906
S2908
S3029
S3073
T3075
Y3077
S3373
S4015
S4076
S4092
T4136
T4148
S4151
S4750
T4754
S4757
S4783
S4804
S4805
T4813
T4828
S4829
S4871
S4989
S4991
S4993
S5022
S5034
T5254
S5526
S5563
S5567
T5569
S5571
S5573
S5669
S5938
S5955
S6201
S6773
S6808
S6812
T6815
S6817
S6829
S6831
S6851
S6881
S6942
S7023
S7075
S7091
S7116
S7178
S7218
S7220
S7232
S7244
S7264
S7265
S7450
S7454
S7654
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S136
S238
T351
S395
T406
S790
S1430
S1483
S2326
S2509
T2613
S2905
T2906
S2908
S3029
S3073
T3075
Y3077
S3373
S4015
S4076
S4092
T4136
T4148
S4151
S4750
T4754
S4757
S4783
S4804
S4805
T4813
T4828
S4829
S4871
S4989
S4991
S4993
S5022
S5034
T5254
S5526
S5563
S5567
T5569
S5571
S5573
S5669
S5938
S5955
S6201
S6773
S6808
S6812
T6815
S6817
S6829
S6831
S6851
S6881
S6942
S7023
S7075
S7091
S7116
S7178
S7218
S7220
S7232
S7244
S7264
S7265
S7450
S7454
S7654
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.