Protein: ENSP00000411355
Gene: PTPRC

LinkedOmicsKB © 2022-2023 Zhang Lab

PTPRC:
protein tyrosine phosphatase receptor type C

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T339TCDTQNITYRFQCGN18----------------53--
Y340CDTQNITYRFQCGNM18----------------53--
S609YDLHKKRSCNLDEQQ18--------------62----
S970GNQEENKSKNRNSNV225----99--------61----
S975NKSKNRNSNVIPYDY101544122-99769710099-10862108991101018319105439518
S994LKHELEMSKESEHDS9125773-10380--99-10862108991101014713105448718
S1001SKESEHDSDESSDDD6207----363517---3429108--51266
S1004SEHDSDESSDDDSDS62357---36358---44381916----266
S1005EHDSDESSDDDSDSE82717---362745-48275443267--266
S1009DESSDDDSDSEEPSK81758---5452-13630268842--72
Showing 1 to 10 of 18 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T339TCDTQNITYRFQCGN-----------
Y340CDTQNITYRFQCGNM-----------
S609YDLHKKRSCNLDEQQ-----------
S970GNQEENKSKNRNSNV-----------
S975NKSKNRNSNVIPYDY5.6e-21-3.9e-156.1e-8-6.1e-130.96-0.280.0415.6e-8-0.73
S994LKHELEMSKESEHDS3.1e-10-3e-27--2.9e-10-0.2-1.8e-60.380.0713.5e-3
S1001SKESEHDSDESSDDD8.3e-11--1.6e-4--6.4e-8----
S1004SEHDSDESSDDDSDS8.4e-10--1.6e-4--9.6e-7----
S1005EHDSDESSDDDSDSE6.5e-10--1.9e-4-5.7e-7-----
S1009DESSDDDSDSEEPSK7.4e-4-----7.4e-4----
Showing 1 to 10 of 18 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationCCRCCT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationCOADT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationGBMT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationHNSCCT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationLSCCT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationLUADT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationOVT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationPDACT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylationUCECT339Y340S609S970S975S994S1001S1004S1005S1009Y1122T1123S1126T1284S1285S1293S1299S1306proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.