Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
7kbu chain A
7kbu chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S59 NEKETAVS TEDDSHH 10 1336 110 - 99 76 76 85 99 - 62 36 94 86 97 89 76 16 100 43 85 7 T60 EKETAVST EDDSHHK 7 122 8 - 12 12 - - - - 5 3 30 28 4 5 - - 2 1 12 - S64 AVSTEDDS HHKAEKS 7 150 - - 8 8 - - 72 - 5 3 5 5 10 8 - - 9 3 12 2 S76 EKSSVLKS KEESHEQ 9 948 95 - 100 80 80 81 81 - 48 26 103 94 4 4 - - 101 43 8 - S80 VLKSKEES HEQSAEQ 10 835 16 - 102 80 72 80 99 - 52 32 10 9 18 16 18 4 81 35 93 18 S84 KEESHEQS AEQGKSS 10 1174 62 - 70 57 89 90 90 - 98 55 93 86 61 57 55 12 83 34 66 16 S90 QSAEQGKS SSQELGL 8 299 32 - 19 17 - - 99 - 6 4 10 8 5 4 - - 52 20 23 - S91 SAEQGKSS SQELGLK 7 311 33 - 3 3 - - 10 - - - 74 70 27 23 - - 27 10 29 2 S92 AEQGKSSS QELGLKD 10 1303 113 - 64 44 85 85 99 - 88 48 78 70 97 89 83 19 89 39 95 18 S127 LDIKEDMS EPQEKKL 1 54 - - - - - - 54 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S59 NEKETAVS TEDDSHH -3.2e-32 - 0.48 -2.3e-9 - -7.1e-6 -5.9e-28 -1.6e-30 -0.022 1.3e-3 - T60 EKETAVST EDDSHHK -8.1e-6 - - - - - -8.1e-6 - - - - S64 AVSTEDDS HHKAEKS - - - - - - - - - - - S76 EKSSVLKS KEESHEQ -1.3e-27 - -0.17 -1.1e-16 - -2.1e-8 -1.1e-27 - - 0.067 - S80 VLKSKEES HEQSAEQ -4.2e-13 - -0.82 -7.4e-15 - -2.7e-11 - - - 2.9e-4 -2.4e-7 S84 KEESHEQS AEQGKSS -7.9e-44 - -0.43 -1.8e-14 - -2.4e-14 -4.9e-26 -5.2e-18 -0.5 0.64 -1.6e-4 S90 QSAEQGKS SSQELGL 0.018 - - - - - - - - 0.018 - S91 SAEQGKSS SQELGLK -9.4e-17 - - - - - -4.1e-21 -1.8e-12 - 0.037 - S92 AEQGKSSS QELGLKD -2.6e-41 - 0.73 -7.9e-12 - -1.3e-12 -1.5e-23 -1.6e-30 -6.2e-7 1.5e-10 -9.8e-6 S127 LDIKEDMS EPQEKKL - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S59
T60
S64
S76
S80
S84
S90
S91
S92
S127
S146
T149
S151
S156
S198
S231
T238
S240
S247
S254
S272
S282
S295
S306
T311
T315
S317
T325
T330
T331
S358
Y361
S413
S414
T419
S420
S421
S543
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation CCRCC S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation COAD S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation GBM S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation HNSCC S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation LSCC S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation LUAD S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation OV S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation PDAC S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation UCEC S59 T60 S64 S76 S80 S84 S90 S91 S92 S127 S146 T149 S151 S156 S198 S231 T238 S240 S247 S254 S272 S282 S295 S306 T311 T315 S317 T325 T330 T331 S358 Y361 S413 S414 T419 S420 S421 S543 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S59
T60
S64
S76
S80
S84
S90
S91
S92
S127
S146
T149
S151
S156
S198
S231
T238
S240
S247
S254
S272
S282
S295
S306
T311
T315
S317
T325
T330
T331
S358
Y361
S413
S414
T419
S420
S421
S543
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S59
T60
S64
S76
S80
S84
S90
S91
S92
S127
S146
T149
S151
S156
S198
S231
T238
S240
S247
S254
S272
S282
S295
S306
T311
T315
S317
T325
T330
T331
S358
Y361
S413
S414
T419
S420
S421
S543
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.