Protein: ENSP00000416959
Gene: TRA2B

LinkedOmicsKB © 2022-2023 Zhang Lab

TRA2B:
transformer 2 beta homolog

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14QNYGERESRSASRSG260----------54--438----
S16YGERESRSASRSGSA824214---1772-12625221212623615--
S18ERESRSASRSGSAHG958455---1772-5428797163556236152614
S20ESRSASRSGSAHGSG628016---101799---2522--62--6518
S22RSASRSGSAHGSGKS10937111-6652293490-63375447928551830136015
S26RSGSAHGSGKSARHT1042438-987282-80419840357121477
S29SAHGSGKSARHTPAR9111488---979999-7442878161557414100418418
T33SGKSARHTPARSRSK847152---635828---28252219771430103411
S37ARHTPARSRSKEDSR788078-69569291--613692837162----7118
S39HTPARSRSKEDSRRS937112-16154336---736641351332-439
Showing 1 to 10 of 27 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14QNYGERESRSASRSG-----------
S16YGERESRSASRSGSA0.68-----6.4e-4---4.6e-3-
S18ERESRSASRSGSAHG2.0e-6----0.0657.6e-103.2e-7--4.6e-30.73
S20ESRSASRSGSAHGSG1.9e-11-----5.4e-13---0.023
S22RSASRSGSAHGSGKS3e-10--0.26-0.17-0.0222.3e-92.1e-24--3.2e-32.5e-4
S26RSGSAHGSGKSARHT1e-12----1.4e-4-3.7e-10---
S29SAHGSGKSARHTPAR-0.25--0.02--0.290.142.2e-31.5e-3-2e-8-1.9e-10
T33SGKSARHTPARSRSK1.3e-6--1.1e-3--1.3e-33.1e-38.4e-50.077-0.001
S37ARHTPARSRSKEDSR0.024--3.0e-44.5e-4-0.277.1e-62.8e-7---3.1e-7
S39HTPARSRSKEDSRRS9.0e-5-----0.0288.4e-4---
Showing 1 to 10 of 27 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationCCRCCS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationCOADS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationGBMS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationHNSCCS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationLSCCS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationLUADS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationOVS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationPDACS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylationUCECS14S16S18S20S22S26S29T33S37S39S43S83S85Y86S87S95S97S99T201T203Y207T212Y213S215Y268S276S278proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.