Protein: ENSP00000417773
Gene: TKT

LinkedOmicsKB © 2022-2023 Zhang Lab

TKT:
transketolase

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S104LLNLRKISSDLDGHP5162------58-63109----3011314
S105LNLRKISSDLDGHPV724732-1211----11645413227--72192
T249TFKGRGITGVEDKES17------------43------
S256TGVEDKESWHGKPLP7693--5348--89-231284778981--54234614
Y275EQIIQEIYSQIQSKK7707--7554--81-1086253499789--177132
S280EIYSQIQSKKKILAT15------5-------------
T287SKKKILATPPQEDAP7962--8260--89-10862108979285--45219518
S295PPQEDAPSVDIANIR71065--9976--90-92531039410596--102429518
S305IANIRMPSLPSYKVG4157------37-22152522------2511
S308IRMPSLPSYKVGDKI145------45-------------
Showing 1 to 10 of 13 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S104LLNLRKISSDLDGHP-0.015---------0.015-
S105LNLRKISSDLDGHPV2.6e-5-----8.3e-49.2e-3---
T249TFKGRGITGVEDKES-----------
S256TGVEDKESWHGKPLP1.2e-3--5.6e-14--0.671.0e-69.9e-15--6.2e-46.7e-9
Y275EQIIQEIYSQIQSKK-4.9e-4-0.49---0.045-6.4e-3-3.3e-3---
S280EIYSQIQSKKKILAT-----------
T287SKKKILATPPQEDAP-0.33--1.8e-3---6.2e-40.410.27--0.980.025
S295PPQEDAPSVDIANIR-0.11--6.4e-15---5.6e-100.616.7e-5-1.3e-30.017
S305IANIRMPSLPSYKVG1.7e-3-----0.118.3e-4---2.3e-4
S308IRMPSLPSYKVGDKI-----------
Showing 1 to 10 of 13 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationCCRCCS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationCOADS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationGBMS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationHNSCCS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationLSCCS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationLUADS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationOVS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationPDACS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylationUCECS104S105T249S256Y275S280T287S295S305S308T342S345T346proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.