PARP14: poly(ADP-ribose) polymerase family member 14
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3goy chain A
3goy chain B
3goy chain C
3goy chain D
3q6z chain A
3q71 chain A
3se2 chain A
3se2 chain B
3se2 chain C
3se2 chain D
3smi chain A
3smi chain B
3smj chain A
3smj chain B
3vfq chain A
4abk chain A
4abl chain A
4d86 chain A
4f1l chain A
4f1l chain B
4f1l chain C
4f1l chain D
4f1q chain A
4f1q chain B
4py4 chain A
4py4 chain B
5lxp chain A
5lxp chain B
5lyh chain A
5lyh chain B
5nqe chain A
5nqe chain B
5o2d chain A
5qht chain A
5qhu chain A
5qhv chain A
5qhw chain A
5qhx chain A
5qhy chain A
5qhz chain A
5qi0 chain A
5qi1 chain A
5qi2 chain A
5qi3 chain A
5qi4 chain A
5qi5 chain A
5qi6 chain A
5qi7 chain A
5qi8 chain A
5qi9 chain A
5qia chain A
5v7t chain A
5v7w chain A
5v7w chain B
6fym chain A
6fym chain B
6fym chain C
6fym chain D
6fzm chain A
6fzm chain B
6g0w chain A
6g0w chain B
6we2 chain A
6we2 chain B
6we3 chain A
6we3 chain B
6we4 chain A
6we4 chain B
7d2c chain A
7l9y chain A
7l9y chain B
7l9y chain C
7l9y chain D
7lun chain A
7lun chain B
7lun chain C
7lun chain D
7lun chain E
7lun chain F
7lun chain G
7lun chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S6 __MAVPGS FPLLVEG 1 8 - - - - - - - - 5 3 - - - - - - - - - - S14 FPLLVEGS WGPDPPK 1 8 - - - - - - - - 5 3 - - - - - - - - - - Y30 LNTKLQMY FQSPKRS 4 34 - - - - 6 3 9 - - - - - 4 4 - - - - 6 2 S33 KLQMYFQS PKRSGGG 9 929 98 - 8 6 36 27 - - 108 62 99 90 93 84 53 13 34 18 84 16 S50 EVRQDPRS PSRFLVF 10 1033 31 - 16 8 44 52 99 - 75 42 88 81 101 92 61 12 95 41 77 18 T92 LTVQLPAT PDEIDHV 5 149 - - 7 7 - - - - 46 25 4 4 26 23 - - - - 7 - S325 LPAPFEES LDLPLWK 5 118 - - - - 13 5 17 - 35 18 - - 12 12 - - 5 1 - - S358 CHCELTWS QLSGKVT 1 8 - - - - - - - - 5 3 - - - - - - - - - - S361 ELTWSQLS GKVTIRP 2 19 - - - - - - - - 7 3 5 4 - - - - - - - - S392 ADTSTTLS SIRSKYK 1 9 - - - - - - - - - - - - 5 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S6 __MAVPGS FPLLVEG - - - - - - - - - - - S14 FPLLVEGS WGPDPPK - - - - - - - - - - - Y30 LNTKLQMY FQSPKRS - - - - - - - - - - - S33 KLQMYFQS PKRSGGG 8.9e-65 - - 1.3e-7 - 4e-20 1.2e-31 2.1e-22 5.8e-3 6.8e-4 3.8e-3 S50 EVRQDPRS PSRFLVF 1.7e-41 - - 4.1e-9 - 5.6e-10 8.4e-7 2.3e-15 0.16 3.4e-13 0.038 T92 LTVQLPAT PDEIDHV -0.71 - - - - -0.98 - -0.63 - - - S325 LPAPFEES LDLPLWK -0.27 - - - - -0.27 - - - - - S358 CHCELTWS QLSGKVT - - - - - - - - - - - S361 ELTWSQLS GKVTIRP - - - - - - - - - - - S392 ADTSTTLS SIRSKYK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S6
S14
Y30
S33
S50
T92
S325
S358
S361
S392
S393
S444
S786
S823
S886
S1007
S1010
T1248
S1249
S1251
S1325
S1396
S1403
S1411
S1592
S1594
S1659
S1688
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation CCRCC S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation COAD S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation GBM S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation HNSCC S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation LSCC S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation LUAD S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation OV S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation PDAC S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation UCEC S6 S14 Y30 S33 S50 T92 S325 S358 S361 S392 S393 S444 S786 S823 S886 S1007 S1010 T1248 S1249 S1251 S1325 S1396 S1403 S1411 S1592 S1594 S1659 S1688 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S6
S14
Y30
S33
S50
T92
S325
S358
S361
S392
S393
S444
S786
S823
S886
S1007
S1010
T1248
S1249
S1251
S1325
S1396
S1403
S1411
S1592
S1594
S1659
S1688
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S6
S14
Y30
S33
S50
T92
S325
S358
S361
S392
S393
S444
S786
S823
S886
S1007
S1010
T1248
S1249
S1251
S1325
S1396
S1403
S1411
S1592
S1594
S1659
S1688
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.