Protein: ENSP00000419446
Gene: ADAM9

LinkedOmicsKB © 2022-2023 Zhang Lab

ADAM9:
ADAM metallopeptidase domain 9

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S733SYFRKKRSQTYESDG7281----5499---3936887147216-
T735FRKKRSQTYESDGKN7179--20125453---201887--84164
S738KRSQTYESDGKNQAN360----126----54--267----
S747GKNQANPSRQPGSVP243--178--18-------------
S752NPSRQPGSVPRHVSP514255-1412--17---1514------132
S758GSVPRHVSPVTPPRE101458122-9472838791-102599387106988319105449518
T761PRHVSPVTPPREVPI1075829-2524494199-703854756783196626362
Y769PPREVPIYANRFAVP81858---13149---302944341084711
S798PPPQPKVSSQGNLIP494--1212--45---109------6-
S799PPQPKVSSQGNLIPA101329112-9673585999-693810895102917617100417718
Showing 1 to 10 of 13 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S733SYFRKKRSQTYESDG1.6e-10-----7.5e-9--1.1e-3-
T735FRKKRSQTYESDGKN1.4e-3-7.2e-3---0.067----
S738KRSQTYESDGKNQAN-----------
S747GKNQANPSRQPGSVP-----------
S752NPSRQPGSVPRHVSP-----------
S758GSVPRHVSPVTPPRE0.011-1.1e-5-7.8e-6-2.4e-31.9e-37e-10-0.56-1.6e-3-0.21
T761PRHVSPVTPPREVPI1.4e-14-3.4e-40.34-4.3e-10-4.3e-10-0.212.1e-3-
Y769PPREVPIYANRFAVP-0.71-----0.43--0.19--
S798PPPQPKVSSQGNLIP-----------
S799PPQPKVSSQGNLIPA1.2e-13-4.2e-3-0.009-5.0e-44.1e-148.0e-42.1e-32.2e-30.83
Showing 1 to 10 of 13 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationCCRCCS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationCOADS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationGBMS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationHNSCCS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationLSCCS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationLUADS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationOVS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationPDACS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylationUCECS733T735S738S747S752S758T761Y769S798S799Y815S817T819proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.