BRD9: bromodomain containing 9
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3hme chain A
3hme chain B
4nqn chain A
4uit chain A
4uiu chain A
4uiv chain A
4uiw chain A
4xy8 chain A
4yy4 chain A
4yy6 chain A
4yyd chain A
4yyg chain A
4yyh chain A
4yyh chain B
4yyi chain A
4yyi chain B
4yyi chain D
4yyi chain E
4yyj chain A
4yyj chain B
4yyj chain D
4yyj chain E
4yyk chain A
4yyk chain B
4yyk chain D
4yyk chain E
4z6h chain A
4z6h chain B
4z6i chain A
4z6i chain B
5e9v chain A
5e9v chain B
5eu1 chain A
5eu1 chain B
5f1h chain A
5f1h chain B
5f1l chain A
5f1l chain B
5f25 chain A
5f25 chain B
5f2p chain A
5f2p chain B
5i40 chain A
5i7x chain A
5i7y chain A
5igm chain A
5igm chain B
5ign chain A
5ign chain B
5ji8 chain A
5mky chain A
5twx chain A
5twx chain B
5twx chain C
5twx chain D
6bqa chain A
6hm0 chain A
6hm0 chain B
6uzf chain A
6v0s chain A
6v0s chain B
6v0x chain A
6v14 chain A
6v1b chain A
6v1b chain B
6y7h chain A
6y7h chain B
6y7i chain A
6y7i chain B
6y7j chain A
6y7j chain B
6y7k chain A
6y7l chain A
6yqr chain AAA
6yqs chain AAA
6yqw chain A
8a7i chain A
8a7i chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14 KHKAEWRS SYEDYAD 1 8 - - - - - - - - - - - - 4 4 - - - - - - S15 HKAEWRSS YEDYADK 4 145 - - - - - - 27 - - - 25 24 15 12 - - - - 30 12 S45 EVTELSGS GHDSSYY 2 16 7 - - - - - 9 - - - - - - - - - - - - - S49 LSGSGHDS SYYDDRS 1 8 - - - - - - - - - - - - - - 7 1 - - - - Y51 GSGHDSSY YDDRSDH 1 9 - - - - - - 9 - - - - - - - - - - - - - Y52 SGHDSSYY DDRSDHE 2 35 - - - - - - 18 - 11 6 - - - - - - - - - - S56 SSYYDDRS DHERERH 2 61 - - - - - - 53 - 5 3 - - - - - - - - - - T103 REREHCDT EGEADDF 10 1480 122 - 103 80 92 96 99 - 108 62 108 99 102 93 53 13 105 44 83 18 T139 QPAENEST PIQQLLE 8 291 - - 4 4 4 5 44 - 72 43 19 18 32 29 6 2 6 3 - - S482 VGDTLGDS SSSVLEF 7 264 - - 4 4 10 8 - - 35 20 29 27 49 46 - - 5 1 24 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14 KHKAEWRS SYEDYAD - - - - - - - - - - - S15 HKAEWRSS YEDYADK -3.4e-3 - - - - - -0.36 - - - -1.3e-3 S45 EVTELSGS GHDSSYY - - - - - - - - - - - S49 LSGSGHDS SYYDDRS - - - - - - - - - - - Y51 GSGHDSSY YDDRSDH - - - - - - - - - - - Y52 SGHDSSYY DDRSDHE - - - - - - - - - - - S56 SSYYDDRS DHERERH - - - - - - - - - - - T103 REREHCDT EGEADDF -1.4e-11 - 7.6e-3 -0.082 - -0.025 -7e-9 -0.023 0.042 -2.1e-10 -6.4e-8 T139 QPAENEST PIQQLLE -3.6e-4 - - - - -8.2e-6 - -0.56 - - - S482 VGDTLGDS SSSVLEF -8.5e-24 - - - - -0.028 -2.6e-14 -2.6e-14 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S14
S15
S45
S49
Y51
Y52
S56
T103
T139
S482
S483
S484
S485
S494
S544
S547
S548
S566
S568
S571
T579
Y583
S588
T597
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation CCRCC S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation COAD S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation GBM S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation HNSCC S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation LSCC S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation LUAD S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation OV S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation PDAC S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation UCEC S14 S15 S45 S49 Y51 Y52 S56 T103 T139 S482 S483 S484 S485 S494 S544 S547 S548 S566 S568 S571 T579 Y583 S588 T597 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S14
S15
S45
S49
Y51
Y52
S56
T103
T139
S482
S483
S484
S485
S494
S544
S547
S548
S566
S568
S571
T579
Y583
S588
T597
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S14
S15
S45
S49
Y51
Y52
S56
T103
T139
S482
S483
S484
S485
S494
S544
S547
S548
S566
S568
S571
T579
Y583
S588
T597
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.