Protein: ENSP00000420195
Gene: SRSF10

LinkedOmicsKB © 2022-2023 Zhang Lab

SRSF10:
serine and arginine rich splicing factor 10

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T21VRNVADDTRSEDLRR19------------54------
S23NVADDTRSEDLRREF91357105-10380838780-1086210899110101--100437018
T92FAQGDRKTPNQMKAK542896-3531--46---44407264------
S106KEGRNVYSSSRYDDY949131-24154517-452815135853--94403415
S108GRNVYSSSRYDDYDR711918-88----1810201744--516-
S119DYDRYRRSRSRSYER3179----7299-----------629
S121DRYRRSRSRSYERRR3179----7299-----------629
S123YRRSRSRSYERRRSR3179----7299-----------629
S129RSYERRRSRSRSFDY91364104-10380949499-98559384110101--101429016
S131YERRRSRSRSFDYNY967625-1679710099-34192018110101--134103
Showing 1 to 10 of 25 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T21VRNVADDTRSEDLRR-----------
S23NVADDTRSEDLRREF1.4e-16--7.4e-191.0e-5-7.8e-128e-171.6e-9-0.010.058
T92FAQGDRKTPNQMKAK6e-26-5.2e-5---2.9e-71.2e-19---
S106KEGRNVYSSSRYDDY1.2e-3-1.0e-5--2.7e-7--0.76--0.25-0.38
S108GRNVYSSSRYDDYDR-0.18------0.18----
S119DYDRYRRSRSRSYER-----------
S121DRYRRSRSRSYERRR-----------
S123YRRSRSRSYERRRSR-----------
S129RSYERRRSRSRSFDY2.7e-29--0.0459.1e-12-4.5e-79.3e-81.8e-19-9.4e-9-0.81
S131YERRRSRSRSFDYNY3.5e-33--9.9e-20-2.6e-50.119.8e-20---
Showing 1 to 10 of 25 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationCCRCCT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationCOADT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationGBMT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationHNSCCT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationLSCCT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationLUADT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationOVT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationPDACT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylationUCECT21S23T92S106S108S119S121S123S129S131S133S141Y142S147S156S158S160S195S197S199S235S249S251S253S256proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.