Protein: ENSP00000420306
Gene: THOC5

LinkedOmicsKB © 2022-2023 Zhang Lab

THOC5:
THO complex 5

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S16RKPKVIRSDGAPAEG68825-42----63--98--52213
S28AEGKRNRSDTEQEGK5332----10890-------67847206418
S307LFKPPEDSQDDESDS8749105-6141626399---73678578--5172
S312EDSQDDESDSDAEEE927630-171410899-1271091717--9215-
S314SQDDESDSDAEEEQT966851-6152181844-5268628072--22118418
T321SDAEEEQTTKRRRPT17----------------52--
T322DAEEEQTTKRRRPTL17----------------52--
T328TTKRRRPTLGVQLDD101527114-103809710099-1086210899105977518105449518
Showing 1 to 8 of 8 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S16RKPKVIRSDGAPAEG-----------
S28AEGKRNRSDTEQEGK-6.9e-8---------0.04-2.5e-8
S307LFKPPEDSQDDESDS4.2e-27--0.0551.4e-7--5.4e-221e-17---
S312EDSQDDESDSDAEEE-----------
S314SQDDESDSDAEEEQT1.5e-23--0.017---5.5e-167.5e-20-0.0116.9e-7
T321SDAEEEQTTKRRRPT-----------
T322DAEEEQTTKRRRPTL-----------
T328TTKRRRPTLGVQLDD-2.9e-3-2.5e-110.91--0.031-0.036-0.0310.9-1.7e-9-3.7e-3
Showing 1 to 8 of 8 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS16S28S307S312S314T321T322T328proteinRNASCNVmethylationCCRCCS16S28S307S312S314T321T322T328proteinRNASCNVmethylationCOADS16S28S307S312S314T321T322T328proteinRNASCNVmethylationGBMS16S28S307S312S314T321T322T328proteinRNASCNVmethylationHNSCCS16S28S307S312S314T321T322T328proteinRNASCNVmethylationLSCCS16S28S307S312S314T321T322T328proteinRNASCNVmethylationLUADS16S28S307S312S314T321T322T328proteinRNASCNVmethylationOVS16S28S307S312S314T321T322T328proteinRNASCNVmethylationPDACS16S28S307S312S314T321T322T328proteinRNASCNVmethylationUCECS16S28S307S312S314T321T322T328proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.