Protein: ENSP00000421925
Gene: MEF2C

LinkedOmicsKB © 2022-2023 Zhang Lab

MEF2C:
myocyte enhancer factor 2C

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S98KGLNGCDSPDPDADD94747-79579928-535510697--1663111
S106PDPDADDSVGHSPES974330-2521343790-452740365952--98419018
S110ADDSVGHSPESEDKY993196-7453384290-107625510697--1054452
S181HPSLQRNSMSPGVTH215------9-----------6-
S183SLQRNSMSPGVTHRP469------18-----54--631815
T187NSMSPGVTHRPPSAG4328-----10-----54----5-
S192GVTHRPPSAGNTGGL716016-88--53---141197--42244
T196RPPSAGNTGGLMGGD439--8---9---------1156-
T205GLMGGDLTSGAGTSA18------8-------------
S222GYGNPRNSPGLLVSP91293122-9978--99-1086210899106975010105449016
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S98KGLNGCDSPDPDADD1.4e-8-2.5e-4----3.3e-6--0.13
S106PDPDADDSVGHSPES-0.16-0.01-8.6e-4--0.75-0.143.4e-3--0.048-0.038
S110ADDSVGHSPESEDKY0.19-1.5e-3-4.4e-3-0.42-1.5e-5--0.011-
S181HPSLQRNSMSPGVTH-----------
S183SLQRNSMSPGVTHRP-----------
T187NSMSPGVTHRPPSAG-----------
S192GVTHRPPSAGNTGGL-----------
T196RPPSAGNTGGLMGGD-----------
T205GLMGGDLTSGAGTSA-----------
S222GYGNPRNSPGLLVSP6.1e-5-1e-18---2.2e-3-0.223.1e-3-6.7e-44.6e-90.51
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationCCRCCS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationCOADS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationGBMS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationHNSCCS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationLSCCS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationLUADS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationOVS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationPDACS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylationUCECS98S106S110S181S183T187S192T196T205S222S228S240S392S396T404S419S445T450S453S459proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.