ARHGEF26: Rho guanine nucleotide exchange factor 26
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S22 TPLWRRRS IPQPHQV 5 195 26 - - - - - 36 - - - 39 38 - - 16 2 - - 36 2 S42 PRPQSYQS PNGLLIT 1 10 - - - - - - - - - - 5 5 - - - - - - - - S80 DSRTVHRS PLLLGAQ 10 1109 122 - 47 43 22 23 90 - 108 62 103 95 106 97 35 8 55 22 53 18 T96 RAVANGGT ASPEYRA 1 8 - - - - - - - - - - - - - - - - - - 6 2 S98 VANGGTAS PEYRAAS 6 540 53 - - - 13 14 99 - - - 94 87 80 72 - - - - 23 5 S124 PKAVPGGS PKSPANG 9 474 33 - 25 24 6 3 62 - 91 53 15 13 63 55 - - 14 5 12 - S127 VPGGSPKS PANGAVT 5 159 6 - - - - - 82 - 6 4 10 10 20 21 - - - - - - T134 SPANGAVT LPAPPPP 1 8 - - - - - - - - - - - - 4 4 - - - - - - T157 PNAPAPCT PEEDLTG 3 102 - - - - - - 54 - - - 5 5 - - - - - - 24 14 S168 DLTGLTAS PVPSPTA 1 18 - - - - - - 18 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S22 TPLWRRRS IPQPHQV -6.1e-4 - - - - - -6.1e-4 - - - - S42 PRPQSYQS PNGLLIT - - - - - - - - - - - S80 DSRTVHRS PLLLGAQ -3.1e-32 - -0.01 -3.1e-6 - -1.1e-5 -2.5e-21 -6.2e-28 - 0.028 -0.16 T96 RAVANGGT ASPEYRA - - - - - - - - - - - S98 VANGGTAS PEYRAAS -1.1e-16 - - - - - -4.9e-8 -3.5e-10 - - - S124 PKAVPGGS PKSPANG -3.8e-22 - -1.6e-5 - - -1.2e-6 - -2.9e-14 - - - S127 VPGGSPKS PANGAVT -1.4e-4 - - - - - - -1.4e-4 - - - T134 SPANGAVT LPAPPPP - - - - - - - - - - - T157 PNAPAPCT PEEDLTG -5.0e-5 - - - - - - - - - -5.0e-5 S168 DLTGLTAS PVPSPTA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S22
S42
S80
T96
S98
S124
S127
T134
T157
S168
S172
T174
S184
S222
S239
S280
S296
S304
S307
S323
S329
S332
S333
S340
T370
S392
S396
S403
S419
S422
S434
S562
S725
S739
S740
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation CCRCC S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation COAD S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation GBM S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation HNSCC S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation LSCC S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation LUAD S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation OV S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation PDAC S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation UCEC S22 S42 S80 T96 S98 S124 S127 T134 T157 S168 S172 T174 S184 S222 S239 S280 S296 S304 S307 S323 S329 S332 S333 S340 T370 S392 S396 S403 S419 S422 S434 S562 S725 S739 S740 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S22
S42
S80
T96
S98
S124
S127
T134
T157
S168
S172
T174
S184
S222
S239
S280
S296
S304
S307
S323
S329
S332
S333
S340
T370
S392
S396
S403
S419
S422
S434
S562
S725
S739
S740
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S22
S42
S80
T96
S98
S124
S127
T134
T157
S168
S172
T174
S184
S222
S239
S280
S296
S304
S307
S323
S329
S332
S333
S340
T370
S392
S396
S403
S419
S422
S434
S562
S725
S739
S740
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.