PLRG1: pleiotropic regulator 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4yvd chain A
5mqf chain D
5xjc chain T
5yzg chain T
5z56 chain T
5z57 chain T
5z58 chain T
6ff4 chain D
6ff7 chain D
6icz chain T
6id0 chain T
6id1 chain T
6qdv chain J
6zym chain D
7aav chain G
7abf chain G
7abg chain G
7abi chain G
7dh6 chain A
7dh6 chain B
7dh6 chain C
7dh6 chain D
7dvq chain T
7w59 chain T
7w5a chain T
7w5b chain T
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S39 PVPLDEES HKRKMAI 1 8 - - 4 4 - - - - - - - - - - - - - - - - S119 TKIQRMPS ESAAQSL 10 1144 98 - 90 69 28 26 73 - 101 59 108 99 110 101 8 1 50 19 95 9 S121 IQRMPSES AAQSLAV 1 8 - - - - 1 7 - - - - - - - - - - - - - - S463 PGSLDSES GIFACAF 1 8 - - 4 4 - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S39 PVPLDEES HKRKMAI - - - - - - - - - - - S119 TKIQRMPS ESAAQSL 1e-8 - 3.0e-4 0.21 - -6.1e-8 8.3e-9 3e-12 - 0.067 - S121 IQRMPSES AAQSLAV - - - - - - - - - - - S463 PGSLDSES GIFACAF - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S39
S119
S121
S463
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S39 S119 S121 S463 protein RNA SCNV methylation CCRCC S39 S119 S121 S463 protein RNA SCNV methylation COAD S39 S119 S121 S463 protein RNA SCNV methylation GBM S39 S119 S121 S463 protein RNA SCNV methylation HNSCC S39 S119 S121 S463 protein RNA SCNV methylation LSCC S39 S119 S121 S463 protein RNA SCNV methylation LUAD S39 S119 S121 S463 protein RNA SCNV methylation OV S39 S119 S121 S463 protein RNA SCNV methylation PDAC S39 S119 S121 S463 protein RNA SCNV methylation UCEC S39 S119 S121 S463 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S39
S119
S121
S463
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S39
S119
S121
S463
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.