SRP19: signal recognition particle 19
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1jid chain A
1mfq chain B
1ry1 chain B
2j37 chain B
3ktv chain B
3ktv chain D
4p3e chain B
5m73 chain B
5m73 chain F
7nfx chain q
7qwq chain q
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S128 KTGGADQS LQQGEGS 2 69 40 - - - - - - - - - 15 14 - - - - - - - - S135 SLQQGEGS KKGKGKK 10 1212 105 - 90 68 42 47 90 - 101 59 98 90 82 77 28 6 83 33 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S128 KTGGADQS LQQGEGS - - - - - - - - - - - S135 SLQQGEGS KKGKGKK 0.006 - -0.83 -0.038 - 2.8e-10 0.19 4.8e-9 - -2.7e-7 0.21
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S128
S135
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S128 S135 protein RNA SCNV methylation CCRCC S128 S135 protein RNA SCNV methylation COAD S128 S135 protein RNA SCNV methylation GBM S128 S135 protein RNA SCNV methylation HNSCC S128 S135 protein RNA SCNV methylation LSCC S128 S135 protein RNA SCNV methylation LUAD S128 S135 protein RNA SCNV methylation OV S128 S135 protein RNA SCNV methylation PDAC S128 S135 protein RNA SCNV methylation UCEC S128 S135 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S128
S135
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S128
S135
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.