ABLIM3: actin binding LIM protein family member 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ujs chain A
2dj7 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S163 EEIKHGQS LLALDKQ 8 694 57 - 87 67 - - 81 - 7 3 45 41 100 93 - - 49 21 27 16 S182 CFKCQTCS VILTGEY 2 27 - - - - - - - - - - 10 9 4 4 - - - - - - T276 KKLKHRRT SETSISP 2 18 - - - - - - - - - - 5 5 - - 6 2 - - - - S277 KLKHRRTS ETSISPP 10 826 48 - 42 37 19 26 71 - 80 47 83 76 65 60 39 12 34 14 57 16 T279 KHRRTSET SISPPGS 3 160 - - 39 20 - - - - - - 35 32 18 16 - - - - - - S280 HRRTSETS ISPPGSS 9 267 8 - 25 16 12 15 18 - 6 3 68 63 8 8 - - 3 2 12 - S282 RTSETSIS PPGSSIG 10 472 58 - 49 37 16 20 91 - 5 2 20 19 26 24 15 3 36 14 33 4 S337 EPHSRYMS DEMLERC 2 52 - - - - - - 44 - 4 4 - - - - - - - - - - S372 DLRQRRAS SPGYIDS 10 695 26 - 18 15 79 91 90 - 54 30 15 14 13 13 63 14 62 26 57 15 S373 LRQRRASS PGYIDSP 10 1213 105 - 28 28 91 97 99 - 62 37 103 95 101 94 68 17 61 26 83 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S163 EEIKHGQS LLALDKQ -0.02 - 2.4e-21 - - - -5.3e-15 -5e-23 - 1.0e-5 -0.89 S182 CFKCQTCS VILTGEY - - - - - - - - - - - T276 KKLKHRRT SETSISP - - - - - - - - - - - S277 KLKHRRTS ETSISPP -7e-17 - 1e-7 - - -1.1e-4 -6.8e-21 -2.5e-11 -4.9e-6 0.48 -2.8e-4 T279 KHRRTSET SISPPGS -4.1e-3 - 1.5e-3 - - - -4.4e-13 - - - - S280 HRRTSETS ISPPGSS -1.7e-4 - 0.26 - - - -1.2e-10 - - - - S282 RTSETSIS PPGSSIG -4.5e-6 - -0.83 - - - -2.2e-5 -8.4e-5 - -0.43 - S337 EPHSRYMS DEMLERC - - - - - - - - - - - S372 DLRQRRAS SPGYIDS -6.2e-13 - - -1e-10 - -1.0e-5 - - -1.1e-4 -0.94 -0.21 S373 LRQRRASS PGYIDSP -1.5e-37 - 9.1e-7 -6.9e-11 - -9.5e-9 -4.6e-30 -2.8e-31 -4.3e-8 2.7e-3 -7.6e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S163
S182
T276
S277
T279
S280
S282
S337
S372
S373
Y376
S379
S388
S392
S394
S405
S409
T421
T461
Y471
S472
Y475
S476
S483
S485
Y487
S493
S503
S504
S514
S537
Y538
T543
S547
S548
S551
Y560
S563
S567
S576
S583
S585
S599
Y605
S607
S650
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation CCRCC S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation COAD S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation GBM S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation HNSCC S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation LSCC S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation LUAD S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation OV S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation PDAC S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation UCEC S163 S182 T276 S277 T279 S280 S282 S337 S372 S373 Y376 S379 S388 S392 S394 S405 S409 T421 T461 Y471 S472 Y475 S476 S483 S485 Y487 S493 S503 S504 S514 S537 Y538 T543 S547 S548 S551 Y560 S563 S567 S576 S583 S585 S599 Y605 S607 S650 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S163
S182
T276
S277
T279
S280
S282
S337
S372
S373
Y376
S379
S388
S392
S394
S405
S409
T421
T461
Y471
S472
Y475
S476
S483
S485
Y487
S493
S503
S504
S514
S537
Y538
T543
S547
S548
S551
Y560
S563
S567
S576
S583
S585
S599
Y605
S607
S650
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S163
S182
T276
S277
T279
S280
S282
S337
S372
S373
Y376
S379
S388
S392
S394
S405
S409
T421
T461
Y471
S472
Y475
S476
S483
S485
Y487
S493
S503
S504
S514
S537
Y538
T543
S547
S548
S551
Y560
S563
S567
S576
S583
S585
S599
Y605
S607
S650
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.