SPOP: speckle type BTB/POZ protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2cr2 chain A
3hqh chain A
3hqi chain A
3hqi chain B
3hql chain A
3hql chain B
3hqm chain A
3hqm chain B
3htm chain A
3htm chain B
3htm chain C
3htm chain D
3hu6 chain A
3hu6 chain B
3ivb chain A
3ivq chain A
3ivq chain B
3ivv chain A
4eoz chain A
4eoz chain C
4hs2 chain A
4j8z chain A
4j8z chain B
4o1v chain A
6f8f chain D
6f8g chain A
6f8g chain B
6f8g chain C
6f8g chain D
6i41 chain A
6i5p chain A
6i5p chain C
6i5p chain E
6i5p chain G
6i68 chain A
6i68 chain C
6i68 chain E
6i68 chain G
6i7a chain A
6i7a chain C
6i7a chain E
6i7a chain G
7d3d chain A
7d3d chain B
7klz chain A
7klz chain B
7lin chain A
7lio chain A
7lio chain B
7lip chain A
7liq chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S6 __MSRVPS PPPPAEM 10 1190 113 - 82 63 26 28 72 - 108 62 103 94 106 97 24 7 73 30 84 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S6 __MSRVPS PPPPAEM 9.9e-7 - -2.8e-3 2.1e-3 - 1.7e-3 1.8e-10 2.6e-5 - -2.4e-3 0.03
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S6
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S6 protein RNA SCNV methylation CCRCC S6 protein RNA SCNV methylation COAD S6 protein RNA SCNV methylation GBM S6 protein RNA SCNV methylation HNSCC S6 protein RNA SCNV methylation LSCC S6 protein RNA SCNV methylation LUAD S6 protein RNA SCNV methylation OV S6 protein RNA SCNV methylation PDAC S6 protein RNA SCNV methylation UCEC S6 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S6
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S6
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.