RNF213: ring finger protein 213
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S19 EETPKFCS QCGERLP 2 17 - - - - - - - - - - 5 5 - - - - 5 2 - - S34 PAAPIADS ENNNSTM 5 93 - - 16 14 - - 17 - 11 6 - - 9 8 - - - - 9 3 S39 ADSENNNS TMASASE 7 672 - - 85 65 - - 62 - 90 52 53 49 77 70 - - 4 1 50 14 T40 DSENNNST MASASEG 7 397 - - 17 14 - - 27 - 35 21 53 49 26 25 - - 34 14 67 15 S43 NNNSTMAS ASEGEME 7 202 - - 4 4 - - 18 - 34 19 20 18 4 4 - - 25 8 30 14 S45 NSTMASAS EGEMECG 7 156 - - 16 16 - - 18 - 6 3 10 9 14 12 - - 13 5 29 5 S67 GPCLFPGS DSWQENP 6 723 - - 77 66 - - - - 72 41 74 68 96 89 - - 79 34 25 2 S69 CLFPGSDS WQENPEE 6 95 - - 14 10 - - - - 6 3 10 9 9 8 - - 10 6 10 - S79 ENPEEPCS KASWTVQ 1 15 - - - - - - - - - - - - - - - - - - 13 2 S266 PSGGRGLS QEGTGPP 6 281 - - 4 2 - - 89 - 25 13 40 36 23 20 - - - - 27 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S19 EETPKFCS QCGERLP - - - - - - - - - - - S34 PAAPIADS ENNNSTM - - - - - - - - - - - S39 ADSENNNS TMASASE 5e-13 - 1.3e-5 - - 2.6e-5 0.82 2.1e-7 - - 0.029 T40 DSENNNST MASASEG 5.6e-10 - - - - 2.4e-6 0.82 5.1e-3 - 0.12 5.5e-6 S43 NNNSTMAS ASEGEME 0.16 - - - - -0.033 0.044 - - - 0.01 S45 NSTMASAS EGEMECG - - - - - - - - - - - S67 GPCLFPGS DSWQENP 1.3e-39 - 3.4e-9 - - 1.1e-8 1.2e-3 1.7e-19 - 2.7e-8 - S69 CLFPGSDS WQENPEE - - - - - - - - - - - S79 ENPEEPCS KASWTVQ - - - - - - - - - - - S266 PSGGRGLS QEGTGPP 0.13 - - - - 0.13 0.63 0.55 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S19
S34
S39
T40
S43
S45
S67
S69
S79
S266
T274
S275
T351
T352
S1177
S1249
S1251
S1254
S1307
S1313
T1719
S1735
T2318
S2322
S2580
S3543
T3544
S3545
S4047
S4470
S4706
S4718
S4735
S4760
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation CCRCC S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation COAD S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation GBM S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation HNSCC S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation LSCC S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation LUAD S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation OV S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation PDAC S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation UCEC S19 S34 S39 T40 S43 S45 S67 S69 S79 S266 T274 S275 T351 T352 S1177 S1249 S1251 S1254 S1307 S1313 T1719 S1735 T2318 S2322 S2580 S3543 T3544 S3545 S4047 S4470 S4706 S4718 S4735 S4760 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S19
S34
S39
T40
S43
S45
S67
S69
S79
S266
T274
S275
T351
T352
S1177
S1249
S1251
S1254
S1307
S1313
T1719
S1735
T2318
S2322
S2580
S3543
T3544
S3545
S4047
S4470
S4706
S4718
S4735
S4760
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S19
S34
S39
T40
S43
S45
S67
S69
S79
S266
T274
S275
T351
T352
S1177
S1249
S1251
S1254
S1307
S1313
T1719
S1735
T2318
S2322
S2580
S3543
T3544
S3545
S4047
S4470
S4706
S4718
S4735
S4760
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.