RACK1: receptor for activated C kinase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4aow chain A
4aow chain B
4aow chain C
4ug0 chain Sg
4v6x chain Ag
5a2q chain g
5aj0 chain Bg
5flx chain g
5lks chain Sg
5oa3 chain g
5t2c chain AI
5vyc chain g1
5vyc chain g2
5vyc chain g3
5vyc chain g4
5vyc chain g5
5vyc chain g6
6fec chain m
6g18 chain g
6g51 chain g
6g53 chain g
6g5h chain g
6g5i chain g
6ip5 chain 3F
6ip6 chain 3F
6ip8 chain 3F
6ole chain Sg
6olf chain Sg
6olg chain Bg
6oli chain Sg
6olz chain Bg
6om0 chain Sg
6om7 chain Sg
6qzp chain Sg
6xa1 chain Sg
6y0g chain Sg
6y2l chain Sg
6y57 chain Sg
6ybs chain c
6z6l chain Sg
6z6m chain Sg
6z6n chain Sg
6zlw chain j
6zm7 chain Sg
6zme chain Sg
6zmi chain Sg
6zmo chain Sg
6zmt chain j
6zmw chain c
6zn5 chain j
6zoj chain g
6zol chain g
6zon chain V
6zp4 chain V
6zuo chain g
6zv6 chain g
6zvh chain g
6zvj chain V
6zxd chain g
6zxe chain g
6zxf chain g
6zxg chain g
6zxh chain g
7a09 chain V
7k5i chain g
7qp6 chain c
7qp7 chain c
7tql chain j
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T24 WVTQIATT PQFPDMI 1 10 - - - - - - - - 7 3 - - - - - - - - - - S160 CVRFSPNS SNPIIVS 2 23 - - - - - - - - - - - - 5 4 - - 9 5 - - S161 VRFSPNSS NPIIVSC 7 855 - - 24 13 - - 64 - 103 60 93 86 88 80 - - 105 44 77 18 S205 VTVSPDGS LCASGGK 1 10 - - - - - - 10 - - - - - - - - - - - - - T252 RYWLCAAT GPSIKIW 1 9 - - - - - - - - - - - - - - - - - - 7 2 S276 ELKQEVIS TSSKAEP 7 628 - - 25 23 - - 27 - 108 62 45 42 71 63 - - 67 29 66 - T277 LKQEVIST SSKAEPP 1 8 - - - - - - - - - - 4 4 - - - - - - - - S278 KQEVISTS SKAEPPQ 5 241 - - - - - - - - 41 24 25 23 9 7 - - 34 12 57 9 S279 QEVISTSS KAEPPQC 2 31 - - - - - - - - 5 4 - - - - - - - - 17 5 T287 KAEPPQCT SLAWSAD 1 9 - - - - - - - - 5 4 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T24 WVTQIATT PQFPDMI - - - - - - - - - - - S160 CVRFSPNS SNPIIVS - - - - - - - - - - - S161 VRFSPNSS NPIIVSC 2.5e-5 - -0.44 - - -0.15 1.1e-24 7.1e-16 - -1.2e-13 0.1 S205 VTVSPDGS LCASGGK - - - - - - - - - - - T252 RYWLCAAT GPSIKIW - - - - - - - - - - - S276 ELKQEVIS TSSKAEP 5.7e-19 - -0.85 - - 1.2e-10 1.7e-19 8.2e-22 - -6.4e-7 - T277 LKQEVIST SSKAEPP - - - - - - - - - - - S278 KQEVISTS SKAEPPQ 0.011 - - - - 0.2 6.5e-14 - - -1.3e-5 - S279 QEVISTSS KAEPPQC - - - - - - - - - - - T287 KAEPPQCT SLAWSAD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T24
S160
S161
S205
T252
S276
T277
S278
S279
T287
S288
S292
T316
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation CCRCC T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation COAD T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation GBM T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation HNSCC T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation LSCC T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation LUAD T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation OV T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation PDAC T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation UCEC T24 S160 S161 S205 T252 S276 T277 S278 S279 T287 S288 S292 T316 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T24
S160
S161
S205
T252
S276
T277
S278
S279
T287
S288
S292
T316
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T24
S160
S161
S205
T252
S276
T277
S278
S279
T287
S288
S292
T316
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.