CEP192: centrosomal protein 192
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4n7z chain B
6fvi chain A
6w3j chain C
7ptb chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S70 YLVEGRFS VPSGSSP 1 6 - - - - - - - - - - - - - - - - - - 6 - S76 FSVPSGSS PGSQSDA 9 421 65 - 25 23 4 5 55 - 21 13 44 40 36 31 - - 17 6 31 5 S79 PSGSSPGS QSDAEPR 1 14 - - - - - - - - - - - - - - - - - - 12 2 S81 GSSPGSQS DAEPRER 1 13 - - - - - - - - - - - - - - - - - - 13 - S92 PRERLQLS FQDDDSI 5 243 56 - - - - - - - 10 8 40 37 45 41 - - - - 6 - S98 LSFQDDDS ISRKKSY 3 119 21 - - - - - - - - - 10 10 42 36 - - - - - - S104 DSISRKKS YVESQRL 4 82 - - - - - - 9 - 18 9 20 17 - - - - - - 7 2 S138 EPAGATES LQGQDLF 1 17 - - - - - - - - - - - - - - - - - - 15 2 S157 PLEQAQDS PIDFHLQ 3 70 6 - - - - - - - - - 29 26 5 4 - - - - - - T195 LKSDLSHT SLLENEK 5 104 15 - - - - - - - - - 15 14 9 7 7 1 - - 27 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S70 YLVEGRFS VPSGSSP - - - - - - - - - - - S76 FSVPSGSS PGSQSDA -0.36 - -0.67 - - 0.53 -0.23 -0.39 - - - S79 PSGSSPGS QSDAEPR - - - - - - - - - - - S81 GSSPGSQS DAEPRER - - - - - - - - - - - S92 PRERLQLS FQDDDSI 2.1e-5 - - - - - 1.7e-3 0.004 - - - S98 LSFQDDDS ISRKKSY 0.48 - - - - - - 0.48 - - - S104 DSISRKKS YVESQRL 3.1e-3 - - - - - 3.1e-3 - - - - S138 EPAGATES LQGQDLF - - - - - - - - - - - S157 PLEQAQDS PIDFHLQ 0.024 - - - - - 0.024 - - - - T195 LKSDLSHT SLLENEK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S70
S76
S79
S81
S92
S98
S104
S138
S157
T195
S196
S269
S281
S284
S287
S290
T321
S328
S329
T331
S371
S444
S457
S492
S499
S501
S510
S512
S565
S580
S612
S711
S804
S806
S812
S863
S866
S883
S899
T902
S906
S917
S944
S959
S963
S1049
S1064
S1078
S1188
S1200
S1749
S1751
S1755
S2085
S2090
S2098
S2110
S2250
S2406
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation CCRCC S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation COAD S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation GBM S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation HNSCC S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation LSCC S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation LUAD S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation OV S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation PDAC S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation UCEC S70 S76 S79 S81 S92 S98 S104 S138 S157 T195 S196 S269 S281 S284 S287 S290 T321 S328 S329 T331 S371 S444 S457 S492 S499 S501 S510 S512 S565 S580 S612 S711 S804 S806 S812 S863 S866 S883 S899 T902 S906 S917 S944 S959 S963 S1049 S1064 S1078 S1188 S1200 S1749 S1751 S1755 S2085 S2090 S2098 S2110 S2250 S2406 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S70
S76
S79
S81
S92
S98
S104
S138
S157
T195
S196
S269
S281
S284
S287
S290
T321
S328
S329
T331
S371
S444
S457
S492
S499
S501
S510
S512
S565
S580
S612
S711
S804
S806
S812
S863
S866
S883
S899
T902
S906
S917
S944
S959
S963
S1049
S1064
S1078
S1188
S1200
S1749
S1751
S1755
S2085
S2090
S2098
S2110
S2250
S2406
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S70
S76
S79
S81
S92
S98
S104
S138
S157
T195
S196
S269
S281
S284
S287
S290
T321
S328
S329
T331
S371
S444
S457
S492
S499
S501
S510
S512
S565
S580
S612
S711
S804
S806
S812
S863
S866
S883
S899
T902
S906
S917
S944
S959
S963
S1049
S1064
S1078
S1188
S1200
S1749
S1751
S1755
S2085
S2090
S2098
S2110
S2250
S2406
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.