SYTL2: synaptotagmin like 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3bc1 chain B
3bc1 chain F
7opp chain A
7opp chain C
7opq chain A
7opq chain B
7opr chain A
7opr chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S75 GADIIRAS MRKKRPQ 1 16 16 - - - - - - - - - - - - - - - - - - - S88 PQIAAEQS KDRENGA 2 93 - - - - - - - - - - - - 27 24 - - 28 14 - - S128 EEDAAPAS PSSSVVN 3 37 - - 4 4 - - - - - - - - 4 5 - - 14 6 - - S130 DAAPASPS SSVVNPA 1 8 - - - - - - - - - - - - - - - - 7 1 - - S132 APASPSSS VVNPASS 1 6 - - - - - - - - - - - - - - - - 4 2 - - S154 NTRKPNVS PEKRKNP 9 675 121 - 7 6 - - 54 - 108 62 59 54 4 4 5 3 105 44 32 7 S192 RTGLFQTS KEDELSE 2 43 9 - - - - - - - - - - - 18 16 - - - - - - S198 TSKEDELS ESKEKST 3 180 88 - - - - - - - - - - - 44 39 - - 7 2 - - S228 LPGLSNGS QIKAPIP 1 8 - - - - - - - - - - - - 4 4 - - - - - - S262 FPRQRTDS LKARGAP 5 295 52 - - - - - - - 11 7 - - 48 44 40 11 57 25 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S75 GADIIRAS MRKKRPQ - - - - - - - - - - - S88 PQIAAEQS KDRENGA 0.073 - - - - - - 0.26 - 0.16 - S128 EEDAAPAS PSSSVVN - - - - - - - - - - - S130 DAAPASPS SSVVNPA - - - - - - - - - - - S132 APASPSSS VVNPASS - - - - - - - - - - - S154 NTRKPNVS PEKRKNP 1.2e-10 - - - - 5.4e-3 1.8e-7 - - 1.6e-3 - S192 RTGLFQTS KEDELSE - - - - - - - - - - - S198 TSKEDELS ESKEKST 6.2e-15 - - - - - - 6.2e-15 - - - S228 LPGLSNGS QIKAPIP - - - - - - - - - - - S262 FPRQRTDS LKARGAP 2.3e-8 - - - - - - 7.3e-7 0.17 8.3e-4 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S75
S88
S128
S130
S132
S154
S192
S198
S228
S262
S277
S278
S279
S280
S281
S301
S316
S321
S322
S344
S390
S460
S466
S488
S493
S511
S517
S519
S520
S535
S562
S571
T576
T578
S580
S582
S583
S595
T597
T886
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation CCRCC S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation COAD S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation GBM S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation HNSCC S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation LSCC S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation LUAD S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation OV S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation PDAC S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation UCEC S75 S88 S128 S130 S132 S154 S192 S198 S228 S262 S277 S278 S279 S280 S281 S301 S316 S321 S322 S344 S390 S460 S466 S488 S493 S511 S517 S519 S520 S535 S562 S571 T576 T578 S580 S582 S583 S595 T597 T886 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S75
S88
S128
S130
S132
S154
S192
S198
S228
S262
S277
S278
S279
S280
S281
S301
S316
S321
S322
S344
S390
S460
S466
S488
S493
S511
S517
S519
S520
S535
S562
S571
T576
T578
S580
S582
S583
S595
T597
T886
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S75
S88
S128
S130
S132
S154
S192
S198
S228
S262
S277
S278
S279
S280
S281
S301
S316
S321
S322
S344
S390
S460
S466
S488
S493
S511
S517
S519
S520
S535
S562
S571
T576
T578
S580
S582
S583
S595
T597
T886
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.