BRSK2: BR serine/threonine kinase 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S294 VQIRSLPS LEDIDPD 2 96 - - - - - - 89 - - - - - - - - - 5 2 - - S367 PPRKRVDS PMLNRHG 4 161 - - - - - - 99 - - - 20 18 9 8 - - 5 2 - - S382 KRRPERKS MEVLSVT 1 81 - - - - - - 81 - - - - - - - - - - - - - S393 LSVTDGGS PVPARRA 2 123 - - - - - - 99 - - - - - - - - - 16 8 - - S410 MAQHGQRS RSISGAS 1 61 - - - - - - 61 - - - - - - - - - - - - - S412 QHGQRSRS ISGASSG 2 118 - - - - - - 45 - - - - - - - - - 51 22 - - S423 ASSGLSTS PLSSPRV 5 211 - - - - - - 90 - 12 7 5 5 5 4 - - 57 26 - - S427 LSTSPLSS PRVTPHP 2 18 - - - - - - 9 - - - - - - - - - 5 4 - - S435 PRVTPHPS PRGSPLP 2 95 - - - - - - 90 - - - - - - - - - 3 2 - - S439 PHPSPRGS PLPTPKG 2 42 - - - - - - 27 - - - - - - - - - 10 5 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S294 VQIRSLPS LEDIDPD - - - - - - - - - - - S367 PPRKRVDS PMLNRHG 5.3e-3 - - - - - 5.3e-3 - - - - S382 KRRPERKS MEVLSVT - - - - - - - - - - - S393 LSVTDGGS PVPARRA - - - - - - - - - - - S410 MAQHGQRS RSISGAS - - - - - - - - - - - S412 QHGQRSRS ISGASSG -3.1e-7 - - - - - - - - -3.1e-7 - S423 ASSGLSTS PLSSPRV -1.3e-7 - - - - - - - - -1.3e-7 - S427 LSTSPLSS PRVTPHP - - - - - - - - - - - S435 PRVTPHPS PRGSPLP - - - - - - - - - - - S439 PHPSPRGS PLPTPKG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S294
S367
S382
S393
S410
S412
S423
S427
S435
S439
T443
T447
T451
S455
T459
T463
S466
S467
S506
T509
S512
S513
S520
S527
S664
T691
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation CCRCC S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation COAD S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation GBM S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation HNSCC S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation LSCC S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation LUAD S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation OV S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation PDAC S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation UCEC S294 S367 S382 S393 S410 S412 S423 S427 S435 S439 T443 T447 T451 S455 T459 T463 S466 S467 S506 T509 S512 S513 S520 S527 S664 T691 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S294
S367
S382
S393
S410
S412
S423
S427
S435
S439
T443
T447
T451
S455
T459
T463
S466
S467
S506
T509
S512
S513
S520
S527
S664
T691
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S294
S367
S382
S393
S410
S412
S423
S427
S435
S439
T443
T447
T451
S455
T459
T463
S466
S467
S506
T509
S512
S513
S520
S527
S664
T691
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.