Protein: ENSP00000432008

RIC8A:: RIC8 guanine nucleotide exchange factor A

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S32	YNQEHSQSFTFDDAQ	2	54	-	-	-	-	3	6	45	-	-	-	-	-	-	-	-	-	-	-	-	-
Y435	GGRPEGQYSEDEDTD	9	657	-	-	9	8	6	3	35	-	108	62	78	72	89	82	12	4	54	21	11	3
S436	GRPEGQYSEDEDTDT	9	971	-	-	66	52	97	100	99	-	59	30	44	40	44	39	42	9	97	40	95	18
T441	QYSEDEDTDTDEYKE	9	1082	-	-	91	68	60	56	73	-	89	53	98	90	85	76	14	2	87	35	87	18
T443	SEDEDTDTDEYKEAK	8	501	-	-	20	17	34	38	64	-	13	6	29	25	43	40	-	-	62	26	68	16
S502	VIQPMGMSPRGHLTS	9	1351	-	-	103	80	64	70	99	-	102	59	108	99	106	97	83	19	105	44	95	18
T517	LQDAMCETMEQQLSS	3	43	-	-	-	-	-	-	18	-	5	3	9	8	-	-	-	-	-	-	-	-
S523	ETMEQQLSSDPDSDP	1	8	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	5	3
S524	TMEQQLSSDPDSDPD	1	8	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	5	3
S528	QLSSDPDSDPD____	5	242	-	-	-	-	-	-	89	-	5	3	34	30	32	28	-	-	-	-	19	2

Showing 1 to 10 of 10 rows

Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S32	YNQEHSQSFTFDDAQ	-	-	-	-	-	-	-	-	-	-	-
Y435	GGRPEGQYSEDEDTD	-0.078	-	-	-	-	-0.67	-0.015	0.44	-	-0.15	-
S436	GRPEGQYSEDEDTDT	2.8e-11	-	-0.3	6.3e-6	-	5.6e-4	5.4e-5	4.6e-4	-	0.56	0.011
T441	QYSEDEDTDTDEYKE	6.3e-31	-	-3.7e-8	1.1e-5	-	1.2e-14	1.1e-19	7.5e-17	-	0.011	5.9e-5
T443	SEDEDTDTDEYKEAK	0.028	-	1.2e-4	0.37	-	-	3.7e-6	0.075	-	-5.8e-3	-2.6e-3
S502	VIQPMGMSPRGHLTS	2.8e-14	-	4.2e-20	0.63	-	3.7e-7	2.9e-5	1.2e-11	0.38	-1.4e-9	0.32
T517	LQDAMCETMEQQLSS	-	-	-	-	-	-	-	-	-	-	-
S523	ETMEQQLSSDPDSDP	-	-	-	-	-	-	-	-	-	-	-
S524	TMEQQLSSDPDSDPD	-	-	-	-	-	-	-	-	-	-	-
S528	QLSSDPDSDPD____	-0.56	-	-	-	-	-	0.95	-0.37	-	-	-

Showing 1 to 10 of 10 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000432008Gene: RIC8A

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000432008
Gene: RIC8A