HSPA8: heat shock protein family A (Hsp70) member 8
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3agy chain C
3agy chain D
3agy chain F
3agz chain C
3agz chain D
3agz chain E
3agz chain F
3esk chain B
3fzf chain A
3fzh chain A
3fzk chain A
3fzl chain A
3fzm chain A
3ldq chain A
3m3z chain A
4h5n chain A
4h5n chain B
4h5r chain A
4h5r chain B
4h5t chain A
4h5v chain A
4h5w chain A
4h5w chain B
4hwi chain A
4kbq chain C
4kbq chain D
5aqf chain A
5aqf chain C
5aqg chain A
5aqg chain C
5aqg chain E
5aqh chain A
5aqi chain A
5aqi chain C
5aqj chain A
5aqj chain C
5aqj chain E
5aqk chain A
5aql chain A
5aql chain C
5aqm chain A
5aqm chain C
5aqn chain A
5aqn chain C
5aqn chain E
5aqo chain A
5aqo chain C
5aqo chain E
5aqp chain A
5aqp chain C
5aqp chain E
5aqq chain A
5aqq chain C
5aqq chain E
5aqr chain A
5aqr chain C
5aqr chain E
5aqs chain A
5aqs chain C
5aqt chain A
5aqu chain A
5aqv chain A
6b1i chain A
6b1i chain B
6b1m chain A
6b1m chain B
6b1n chain A
6b1n chain B
6zyj chain A
6zyj chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y15 GIDLGTTY SCVGVFQ 2 72 - - - - - - 45 - 15 12 - - - - - - - - - - S85 FDDAVVQS DMKHWPF 7 201 55 - 9 8 - - 27 - - - 19 17 25 23 - - 8 4 6 - S113 EYKGETKS FYPEEVS 6 120 7 - 16 6 - - - - 11 8 20 20 9 9 - - - - 12 2 S121 FYPEEVSS MVLTKMK 1 8 - - - - - - - - - - - - - - - - - - 6 2 T138 AEAYLGKT VTNAVVT 2 23 - - - - - - 8 - - - - - - - - - - - 11 4 T140 AYLGKTVT NAVVTVP 3 65 - - - - - - 18 - 5 4 - - - - - - - - 33 5 S153 VPAYFNDS QRQATKD 3 55 - - - - - - 27 - - - - - - - 6 2 - - 18 2 S254 RKHKKDIS ENKRAVR 5 303 8 - - - - - 44 - - - 40 35 52 47 - - 53 24 - - S329 RDAKLDKS QIHDIVL 7 242 14 - 4 4 15 21 90 - 30 17 5 5 - - - - - - 33 4 S340 DIVLVGGS TRIPKIQ 1 27 - - - - - - 27 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y15 GIDLGTTY SCVGVFQ - - - - - - - - - - - S85 FDDAVVQS DMKHWPF 0.028 - - - - - - 0.028 - - - S113 EYKGETKS FYPEEVS 1.6e-3 - - - - - 1.6e-3 - - - - S121 FYPEEVSS MVLTKMK - - - - - - - - - - - T138 AEAYLGKT VTNAVVT - - - - - - - - - - - T140 AYLGKTVT NAVVTVP - - - - - - - - - - - S153 VPAYFNDS QRQATKD - - - - - - - - - - - S254 RKHKKDIS ENKRAVR 1.8e-16 - - - - - 1.5e-7 3.5e-11 - 0.017 - S329 RDAKLDKS QIHDIVL -1.6e-3 - - - - -1.6e-3 - - - - - S340 DIVLVGGS TRIPKIQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y15
S85
S113
S121
T138
T140
S153
S254
S329
S340
S362
S381
S432
S511
Y525
S541
S544
Y545
S613
S633
S637
S638
T641
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation CCRCC Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation COAD Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation GBM Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation HNSCC Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation LSCC Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation LUAD Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation OV Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation PDAC Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation UCEC Y15 S85 S113 S121 T138 T140 S153 S254 S329 S340 S362 S381 S432 S511 Y525 S541 S544 Y545 S613 S633 S637 S638 T641 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y15
S85
S113
S121
T138
T140
S153
S254
S329
S340
S362
S381
S432
S511
Y525
S541
S544
Y545
S613
S633
S637
S638
T641
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y15
S85
S113
S121
T138
T140
S153
S254
S329
S340
S362
S381
S432
S511
Y525
S541
S544
Y545
S613
S633
S637
S638
T641
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.