CKAP5: cytoskeleton associated protein 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4qmi chain A
4qmi chain B
4qmj chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S247 AKLEQQQS AGGDAEG 1 9 - - - - - - 9 - - - - - - - - - - - - - S430 SFRHCTAS TLPKSLL 1 6 - - - - - - - - - - - - - - - - - - 6 - T431 FRHCTAST LPKSLLK 1 6 - - - - - - - - - - - - - - - - - - 6 - T569 APGGAGNT GTKNKKG 9 635 76 - 58 39 - - 53 - 58 31 44 41 77 73 15 2 30 13 25 - T571 GGAGNTGT KNKKGLE 1 10 - - - - - - 10 - - - - - - - - - - - - - S588 EIVEPELS IEVCEEK 2 17 - - - - - - 8 - 5 4 - - - - - - - - - - S816 FEKMQGQS PPAPTRG 9 484 87 - 4 4 - - 71 - 55 33 30 28 58 52 22 5 5 2 24 4 T829 RGISKHST SGTDEGE 1 5 - - - - - - - - - - - - - - - - 4 1 - - S830 GISKHSTS GTDEGED 8 314 34 - 7 7 - - 99 - 33 19 10 9 29 23 - - 17 7 17 3 T832 SKHSTSGT DEGEDGD 10 906 89 - 49 37 26 18 88 - 108 62 73 66 58 53 59 14 49 19 29 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S247 AKLEQQQS AGGDAEG - - - - - - - - - - - S430 SFRHCTAS TLPKSLL - - - - - - - - - - - T431 FRHCTAST LPKSLLK - - - - - - - - - - - T569 APGGAGNT GTKNKKG -0.68 - 2.6e-7 - - 2.4e-4 -4.4e-7 -2.9e-8 - 0.39 - T571 GGAGNTGT KNKKGLE - - - - - - - - - - - S588 EIVEPELS IEVCEEK - - - - - - - - - - - S816 FEKMQGQS PPAPTRG 6.1e-15 - - - - 7.5e-4 1.9e-5 4.5e-9 - - - T829 RGISKHST SGTDEGE - - - - - - - - - - - S830 GISKHSTS GTDEGED 0.96 - - - - 0.52 - -0.57 - - - T832 SKHSTSGT DEGEDGD -0.069 - -0.86 -0.3 - 0.069 -0.014 -0.46 0.07 -5.2e-5 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S247
S430
T431
T569
T571
S588
S816
T829
S830
T832
S845
S953
T964
S984
S1115
S1149
S1157
S1428
S1469
S1471
S1528
S1801
T1805
S1807
S1809
Y1860
S1861
S1904
T1914
S1964
S1973
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation CCRCC S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation COAD S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation GBM S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation HNSCC S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation LSCC S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation LUAD S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation OV S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation PDAC S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation UCEC S247 S430 T431 T569 T571 S588 S816 T829 S830 T832 S845 S953 T964 S984 S1115 S1149 S1157 S1428 S1469 S1471 S1528 S1801 T1805 S1807 S1809 Y1860 S1861 S1904 T1914 S1964 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S247
S430
T431
T569
T571
S588
S816
T829
S830
T832
S845
S953
T964
S984
S1115
S1149
S1157
S1428
S1469
S1471
S1528
S1801
T1805
S1807
S1809
Y1860
S1861
S1904
T1914
S1964
S1973
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S247
S430
T431
T569
T571
S588
S816
T829
S830
T832
S845
S953
T964
S984
S1115
S1149
S1157
S1428
S1469
S1471
S1528
S1801
T1805
S1807
S1809
Y1860
S1861
S1904
T1914
S1964
S1973
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.