Protein: ENSP00000433664
Gene: EIF4G2

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF4G2:
eukaryotic translation initiation factor 4 gamma 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14EGGASRFSASSGGGG6229--54--9-63382422--358--183
S16GASRFSASSGGGGSR835421-44--27-6373664944214--239
S17ASRFSASSGGGGSRG101336122-9168637153-108621089610192419102428918
S22ASSGGGGSRGAPQHY864917-67539917-412074689385--6927--
S62STRRDDNSAANNSAN19------------------72
S67DNSAANNSANEKERH4216------9---25246456--2711--
S272LDHERAKSLMDQYFA19------------------72
S381MFGQMPGSGIGTGPG772795-10380711--895065548877--71--
T385MPGSGIGTGPGVIQD6260--2926--18-623619182020--84--
S395GVIQDRFSPTMGRHR101505114-90689710099-1086210394110968319105449518
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14EGGASRFSASSGGGG1.4e-3----6.2e-50.61----
S16GASRFSASSGGGGSR-1.4e-17------1.1e-11-1.3e-7---
S17ASRFSASSGGGGSRG5.5e-45-1.9e-40.24-1.4e-92.1e-316.2e-10-2.3e-120.16
S22ASSGGGGSRGAPQHY0.03-0.72--8.7e-90.440.065--1.1e-4-
S62STRRDDNSAANNSAN-----------
S67DNSAANNSANEKERH-0.73-----0.20.021--2.8e-3-
S272LDHERAKSLMDQYFA-----------
S381MFGQMPGSGIGTGPG1.9e-7-1.3e-10--0.580.150.044---
T385MPGSGIGTGPGVIQD-0.48-5.2e-4---8.4e-3--0.04---
S395GVIQDRFSPTMGRHR3.9e-30-2.4e-16-0.17-7.4e-49.1e-33.7e-46.8e-76.6e-151.8e-3
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationCCRCCS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationCOADS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationGBMS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationHNSCCS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationLSCCS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationLUADS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationOVS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationPDACS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylationUCECS14S16S17S22S62S67S272S381T385S395T397S436S443S454S479S500T506T508T514S602proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.