Protein: ENSP00000434024

H2AX:: H2A.X variant histone

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait

				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
T121	AVLLPKKTSATVGPK	8	255	6	-	12	12	-	-	18	-	5	3	64	58	14	11	27	7	13	5	-	-
S122	VLLPKKTSATVGPKA	10	569	9	-	4	4	7	2	90	-	40	22	35	34	12	11	83	18	79	33	77	9
T124	LPKKTSATVGPKAPS	2	25	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	5	2	15	3
T137	PSGGKKATQASQEY_	6	219	-	-	4	4	11	7	-	-	-	-	68	57	9	8	7	1	-	-	30	13
S140	GKKATQASQEY____	10	1512	122	-	95	72	97	99	99	-	108	62	108	99	110	101	72	17	101	43	89	18
Y143	ATQASQEY_______	10	1257	113	-	95	71	50	48	90	-	84	50	98	89	105	97	40	11	91	38	74	13

Showing 1 to 6 of 6 rows

Tumor and normal comparison

Loading, please wait

Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
T121	AVLLPKKTSATVGPK	-7.6e-17	-	-	-	-	-	-7.5e-17	-	-	-	-
S122	VLLPKKTSATVGPKA	2.3e-15	-	-	-	-	5.4e-6	6.6e-11	-	4.6e-5	0.49	-
T124	LPKKTSATVGPKAPS	-	-	-	-	-	-	-	-	-	-	-
T137	PSGGKKATQASQEY_	2.5e-6	-	-	-	-	-	4.7e-10	-	-	-	0.67
S140	GKKATQASQEY____	1e-39	-	8.9e-16	3.9e-22	-	1.2e-8	8.2e-22	1.0e-6	-0.77	-0.24	0.38
Y143	ATQASQEY_______	1.8e-35	-	1.1e-15	5e-15	-	2.6e-9	1.1e-15	-0.12	0.13	2.3e-11	-0.19

Showing 1 to 6 of 6 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait

			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait

			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait

			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000434024Gene: H2AX

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000434024
Gene: H2AX