TXNRD1: thioredoxin reductase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2cfy chain A
2cfy chain B
2cfy chain C
2cfy chain D
2cfy chain E
2cfy chain F
2j3n chain A
2j3n chain B
2j3n chain C
2j3n chain D
2j3n chain E
2j3n chain F
2zz0 chain A
2zz0 chain B
2zz0 chain C
2zz0 chain D
2zzb chain A
2zzb chain B
2zzb chain C
2zzb chain D
2zzc chain A
2zzc chain B
2zzc chain C
2zzc chain D
3qfa chain A
3qfa chain B
3qfb chain A
3qfb chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y163 DLPKSYDY DLIIIGG 2 250 - - - - - - - - - - 55 50 77 68 - - - - - - Y281 KVVYENAY GQFIGPH 1 8 - - 4 4 - - - - - - - - - - - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y163 DLPKSYDY DLIIIGG -0.31 - - - - - -0.25 -0.77 - - - Y281 KVVYENAY GQFIGPH - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
Y163
Y281
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y163 Y281 protein RNA SCNV methylation CCRCC Y163 Y281 protein RNA SCNV methylation COAD Y163 Y281 protein RNA SCNV methylation GBM Y163 Y281 protein RNA SCNV methylation HNSCC Y163 Y281 protein RNA SCNV methylation LSCC Y163 Y281 protein RNA SCNV methylation LUAD Y163 Y281 protein RNA SCNV methylation OV Y163 Y281 protein RNA SCNV methylation PDAC Y163 Y281 protein RNA SCNV methylation UCEC Y163 Y281 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
Y163
Y281
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
Y163
Y281
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.