USP36: ubiquitin specific peptidase 36
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S18 LKPGRKDS ADDGELG 10 961 30 - 40 39 54 62 44 - 49 30 88 80 105 97 32 10 86 40 59 16 S75 EGASRHKS GDDPPAR 2 47 - - - - - - - - - - 20 18 5 4 - - - - - - S429 RIPGSKKS PEGLISR 1 6 - - - - - - - - - - - - - - - - - - 6 - S439 GLISRTGS SSLPGRP 2 23 - - - - - - - - - - 5 5 - - - - - - 13 - S464 IGNGIISS PLTGKRQ 7 481 64 - 27 19 - - - - - - 30 26 93 85 41 9 4 2 63 18 S494 VPISRNGS TLGLKSQ 3 37 9 - - - - - - - - - - - - - - - 5 2 19 2 S513 PPKLPSGS PSPKLSQ 2 41 15 - - - - - - - - - 14 12 - - - - - - - - T521 PSPKLSQT PTHMPTI 1 19 - - - - - - - - - - - - - - - - - - 17 2 S546 PAPPQHFS PRTAQGL 7 323 89 - - - 23 13 18 - - - 34 31 4 4 - - 47 20 26 14 S571 SGSQRQGS WDSRDVV 7 277 8 - 8 - - - - - 19 9 40 37 50 43 29 6 - - 22 6
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S18 LKPGRKDS ADDGELG 1.6e-6 - 3.8e-4 1.6e-9 - 2.3e-6 -0.67 5.4e-5 -0.57 -0.013 -0.2 S75 EGASRHKS GDDPPAR 5.8e-9 - - - - - 5.8e-9 - - - - S429 RIPGSKKS PEGLISR - - - - - - - - - - - S439 GLISRTGS SSLPGRP - - - - - - - - - - - S464 IGNGIISS PLTGKRQ 2.1e-16 - 0.3 - - - 2.2e-9 5.1e-15 - - 0.11 S494 VPISRNGS TLGLKSQ - - - - - - - - - - - S513 PPKLPSGS PSPKLSQ - - - - - - - - - - - T521 PSPKLSQT PTHMPTI - - - - - - - - - - - S546 PAPPQHFS PRTAQGL 1.5e-5 - - 5.9e-7 - - 1.5e-6 - - -2.6e-4 0.013 S571 SGSQRQGS WDSRDVV 1.6e-15 - - - - - 4.9e-10 4.6e-7 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S18
S75
S429
S439
S464
S494
S513
T521
S546
S571
S580
T581
S582
S610
S611
S612
S613
S614
S640
S667
S679
T680
S682
S713
S716
T719
S742
S756
S793
S807
S871
S939
S952
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation CCRCC S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation COAD S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation GBM S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation HNSCC S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation LSCC S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation LUAD S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation OV S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation PDAC S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation UCEC S18 S75 S429 S439 S464 S494 S513 T521 S546 S571 S580 T581 S582 S610 S611 S612 S613 S614 S640 S667 S679 T680 S682 S713 S716 T719 S742 S756 S793 S807 S871 S939 S952 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S18
S75
S429
S439
S464
S494
S513
T521
S546
S571
S580
T581
S582
S610
S611
S612
S613
S614
S640
S667
S679
T680
S682
S713
S716
T719
S742
S756
S793
S807
S871
S939
S952
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S18
S75
S429
S439
S464
S494
S513
T521
S546
S571
S580
T581
S582
S610
S611
S612
S613
S614
S640
S667
S679
T680
S682
S713
S716
T719
S742
S756
S793
S807
S871
S939
S952
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.