NNMT: nicotinamide N-methyltransferase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2iip chain A
2iip chain B
2iip chain C
2iip chain D
3rod chain A
3rod chain B
3rod chain C
3rod chain D
5yjf chain A
5yjf chain B
5yjf chain C
5yjf chain D
6chh chain A
6chh chain B
6chh chain C
6chh chain D
6orr chain A
6orr chain B
6orr chain C
6orr chain D
6pve chain A
6pve chain B
6pve chain C
6pve chain D
6pvs chain A
6pvs chain B
6pvs chain C
6pvs chain D
7bkg chain A
7bkg chain B
7bkg chain C
7bkg chain D
7ble chain A
7ble chain B
7ble chain C
7ble chain D
7egu chain A
7ehz chain A
7ei2 chain A
7et7 chain A
7et7 chain B
7et7 chain C
7et7 chain D
7eu5 chain A
7eu5 chain B
7eu5 chain C
7eu5 chain D
7nbj chain A
7nbj chain B
7nbj chain C
7nbj chain D
7nbm chain A
7nbm chain B
7nbm chain C
7nbm chain D
7nbq chain A
7nbq chain B
7nbq chain C
7nbq chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S108 EPEAFDWS PVVTYVC 2 25 - - 13 4 - - 8 - - - - - - - - - - - - - S146 LKCDVTQS QPLGAVP 3 33 9 - 8 8 - - - - - - - - 4 4 - - - - - - S213 IGEQKFSS LPLGREA 1 24 - - 16 8 - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S108 EPEAFDWS PVVTYVC - - - - - - - - - - - S146 LKCDVTQS QPLGAVP - - - - - - - - - - - S213 IGEQKFSS LPLGREA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S108
S146
S213
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S108 S146 S213 protein RNA SCNV methylation CCRCC S108 S146 S213 protein RNA SCNV methylation COAD S108 S146 S213 protein RNA SCNV methylation GBM S108 S146 S213 protein RNA SCNV methylation HNSCC S108 S146 S213 protein RNA SCNV methylation LSCC S108 S146 S213 protein RNA SCNV methylation LUAD S108 S146 S213 protein RNA SCNV methylation OV S108 S146 S213 protein RNA SCNV methylation PDAC S108 S146 S213 protein RNA SCNV methylation UCEC S108 S146 S213 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S108
S146
S213
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S108
S146
S213
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.