FKBP5: FKBP prolyl isomerase 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1kt0 chain A
3o5d chain A
3o5d chain B
3o5e chain A
3o5f chain A
3o5g chain A
3o5i chain A
3o5i chain B
3o5j chain A
3o5k chain A
3o5k chain B
3o5k chain C
3o5k chain D
3o5l chain A
3o5m chain A
3o5m chain B
3o5o chain A
3o5p chain A
3o5q chain A
3o5r chain A
4drh chain A
4drh chain D
4dri chain A
4drk chain A
4drk chain B
4drm chain A
4drn chain A
4dro chain A
4drp chain A
4drq chain A
4jfi chain A
4jfj chain A
4jfk chain A
4jfl chain A
4jfm chain A
4r0x chain A
4tw6 chain A
4tw7 chain A
4tx0 chain A
4w9o chain A
4w9o chain E
4w9p chain A
4w9p chain E
4w9q chain A
5bxj chain A
5dit chain A
5diu chain A
5div chain A
5njx chain A
5obk chain A
5omp chain A
6saf chain A
6tx4 chain A
6tx5 chain A
6tx6 chain A
6tx7 chain A
6tx8 chain A
6tx9 chain A
6txx chain A
6txx chain B
7a6w chain AAA
7a6w chain BBB
7a6x chain AAA
7aot chain A
7aou chain A
7apq chain A
7aps chain A
7aps chain B
7apt chain A
7apw chain A
7awf chain A
7awx chain A
7awx chain B
7b9y chain A
7b9z chain A
7ba0 chain A
7ett chain A
7etu chain A
7etv chain A
7l7i chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S13 GAKNNEES PTATVAE 10 544 30 - 31 23 22 23 99 - 4 4 38 35 8 8 14 2 73 29 83 18 T15 KNNEESPT ATVAEQG 10 650 82 - 43 40 13 14 63 - 38 24 44 38 54 48 25 8 25 10 63 18 T17 NEESPTAT VAEQGED 5 58 9 - 5 4 - - - - 6 3 - - - - 13 3 11 4 - - S115 KPEYAYGS AGSLPKI 1 9 9 - - - - - - - - - - - - - - - - - - - S348 DKALGLDS ANEKGLY 1 9 9 - - - - - - - - - - - - - - - - - - - S434 KAMGKKTS EGVTNEK 9 453 25 - 17 16 - - 26 - 93 52 34 31 4 4 27 8 76 33 5 2 S445 TNEKGTDS QAMEEEK 10 1436 105 - 99 76 68 67 99 - 108 62 98 89 110 101 83 19 98 41 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S13 GAKNNEES PTATVAE -0.065 - 1.0e-4 0.99 - - -4.9e-11 - - 5.0e-4 -8.2e-7 T15 KNNEESPT ATVAEQG -0.05 - 1.6e-3 - - 0.045 -1.6e-3 -0.54 - -0.038 -3.6e-5 T17 NEESPTAT VAEQGED - - - - - - - - - - - S115 KPEYAYGS AGSLPKI - - - - - - - - - - - S348 DKALGLDS ANEKGLY - - - - - - - - - - - S434 KAMGKKTS EGVTNEK 0.25 - - - - 2.3e-10 -0.5 - - -2.2e-4 - S445 TNEKGTDS QAMEEEK 5.5e-32 - 5.3e-18 4.4e-11 - 5.4e-11 7.2e-4 7.5e-9 5.4e-5 4.7e-3 -5.9e-6
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S13
T15
T17
S115
S348
S434
S445
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation CCRCC S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation COAD S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation GBM S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation HNSCC S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation LSCC S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation LUAD S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation OV S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation PDAC S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation UCEC S13 T15 T17 S115 S348 S434 S445 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S13
T15
T17
S115
S348
S434
S445
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S13
T15
T17
S115
S348
S434
S445
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.