RABEP1: rabaptin, RAB GTPase binding effector protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1p4u chain B
1tu3 chain F
1tu3 chain G
1tu3 chain H
1tu3 chain I
1tu3 chain J
1x79 chain B
1x79 chain C
4n3y chain B
4n3y chain C
4n3z chain B
4n3z chain C
4q9u chain C
4q9u chain D
4q9u chain G
4q9u chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S162 ADLRRRLS EGQEEEN 7 227 29 - 4 4 - - 53 - 27 17 20 18 18 16 - - - - 17 4 S246 AVLNTQKS VLQEDAE 6 262 8 - 20 17 - - - - - - 30 26 45 40 - - 26 10 27 13 S357 CALTQEES SAQLSNE 1 9 - - - - - - - - 7 2 - - - - - - - - - - S358 ALTQEESS AQLSNEE 2 17 - - - - - - - - 5 2 - - - - - - 9 1 - - S362 EESSAQLS NEEEHLD 5 87 - - 4 4 - - 53 - 6 4 - - - - - - 9 1 6 - S370 NEEEHLDS TRGSVHS 1 9 9 - - - - - - - - - - - - - - - - - - - T371 EEEHLDST RGSVHSL 1 8 8 - - - - - - - - - - - - - - - - - - - S374 HLDSTRGS VHSLDAG 10 651 105 - 77 58 65 69 19 - 6 3 84 76 4 3 33 7 4 2 32 4 S377 STRGSVHS LDAGLLL 10 1135 95 - 90 68 78 74 36 - 108 62 98 89 106 97 24 8 56 23 23 - S393 SGDPFSKS DNDMFKD 3 98 - - - - - - 27 - 6 4 - - - - - - - - 52 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S162 ADLRRRLS EGQEEEN -0.44 - - - - -0.53 -0.63 - - - - S246 AVLNTQKS VLQEDAE -0.2 - 0.99 - - - 0.2 0.23 - -0.27 -1.9e-5 S357 CALTQEES SAQLSNE - - - - - - - - - - - S358 ALTQEESS AQLSNEE - - - - - - - - - - - S362 EESSAQLS NEEEHLD - - - - - - - - - - - S370 NEEEHLDS TRGSVHS - - - - - - - - - - - T371 EEEHLDST RGSVHSL - - - - - - - - - - - S374 HLDSTRGS VHSLDAG 0.16 - 2.1e-14 -1.1e-9 - - -7.5e-5 - - - - S377 STRGSVHS LDAGLLL 0.46 - 3.1e-12 -0.005 - -0.24 -9.2e-6 -0.059 - 0.13 - S393 SGDPFSKS DNDMFKD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S162
S246
S357
S358
S362
S370
T371
S374
S377
S393
S407
T408
S410
T413
S414
S416
S430
S447
T454
S456
S459
S464
T469
T480
T486
S488
S491
T494
S511
T513
S651
T761
S778
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation CCRCC S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation COAD S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation GBM S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation HNSCC S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation LSCC S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation LUAD S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation OV S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation PDAC S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation UCEC S162 S246 S357 S358 S362 S370 T371 S374 S377 S393 S407 T408 S410 T413 S414 S416 S430 S447 T454 S456 S459 S464 T469 T480 T486 S488 S491 T494 S511 T513 S651 T761 S778 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S162
S246
S357
S358
S362
S370
T371
S374
S377
S393
S407
T408
S410
T413
S414
S416
S430
S447
T454
S456
S459
S464
T469
T480
T486
S488
S491
T494
S511
T513
S651
T761
S778
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S162
S246
S357
S358
S362
S370
T371
S374
S377
S393
S407
T408
S410
T413
S414
S416
S430
S447
T454
S456
S459
S464
T469
T480
T486
S488
S491
T494
S511
T513
S651
T761
S778
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.