BAZ2A: bromodomain adjacent to zinc finger domain 2A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4lz2 chain A
4q6f chain A
4q6f chain B
4q6f chain C
4q6f chain D
4qbm chain A
4qbm chain B
4qf2 chain A
4qf2 chain B
4qf2 chain C
4qf2 chain D
5agq chain A
5mgj chain A
5mgk chain A
5mgl chain A
5mgm chain A
5or8 chain A
5t8r chain A
5t8r chain B
5t8r chain C
5t8r chain D
6fap chain A
6fap chain B
6fap chain C
6fap chain D
6fg6 chain A
6fgf chain A
6fgg chain A
6fgh chain A
6fgi chain A
6fgl chain A
6fgv chain A
6fgw chain A
6fhu chain A
6fhu chain B
6fhu chain C
6fhu chain D
6fi0 chain A
6fi0 chain B
6fi0 chain C
6fi0 chain D
6fkp chain A
6fkp chain B
6fkp chain C
6fkp chain D
7b7b chain A
7b7g chain A
7b7i chain A
7b82 chain A
7bc2 chain A
7bl8 chain A
7bl9 chain A
7bla chain A
7blb chain A
7blc chain A
7bld chain A
7fhj chain A
7fhj chain B
7mwi chain A
7mwl chain A
7mwl chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S38 EGLYTNGS PMNFPQQ 1 5 - - - - - - - - - - - - - - - - 4 1 - - S117 PPLLSQFS GGQYPLN 4 211 - - - - - - - - 23 12 20 18 58 53 - - - - 23 4 S135 GGSRQPSS PSHNTNL 7 352 17 - - - 44 45 89 - 41 20 10 9 - - 57 14 - - 6 - S496 SVTSPKAS PVTSPAA 10 644 75 - 32 22 27 18 18 - 83 51 44 42 34 32 52 12 35 15 39 13 S500 PKASPVTS PAAAFPT 8 420 17 - 4 4 23 22 - - 59 32 34 31 37 32 - - 34 16 59 16 T507 SPAAAFPT ASPANKD 7 380 95 - 77 65 - - - - 15 9 15 13 36 32 - - 11 5 7 - S509 AAAFPTAS PANKDVS 9 429 6 - - - 68 58 63 - 6 3 5 4 8 9 34 6 40 20 90 9 S536 TGEGLTAS GSGDVMR 1 9 - - - - - - - - - - 5 4 - - - - - - - - S604 LSRNVVHS VRREHFS 1 18 - - - - - - - - - - - - 10 8 - - - - - - T1050 SSRIMEET SGMEEEE 2 49 13 - - - - - - - - - 19 17 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S38 EGLYTNGS PMNFPQQ - - - - - - - - - - - S117 PPLLSQFS GGQYPLN -8.1e-3 - - - - -0.12 -0.32 -0.041 - - - S135 GGSRQPSS PSHNTNL 8.7e-6 - - 1.1e-5 - 0.035 - - 0.23 - - S496 SVTSPKAS PVTSPAA 1.3e-15 - 0.76 0.3 - 1.9e-3 1.6e-16 2.4e-5 -0.55 0.43 4.2e-8 S500 PKASPVTS PAAAFPT 0.061 - - 0.071 - -0.32 -0.83 2.9e-3 - -0.7 0.16 T507 SPAAAFPT ASPANKD 1.4e-16 - 8.2e-5 - - - - 9.5e-15 - - - S509 AAAFPTAS PANKDVS 0.78 - - 0.78 - - - - - 1 - S536 TGEGLTAS GSGDVMR - - - - - - - - - - - S604 LSRNVVHS VRREHFS - - - - - - - - - - - T1050 SSRIMEET SGMEEEE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S38
S117
S135
S496
S500
T507
S509
S536
S604
T1050
S1051
S1183
S1184
S1207
S1214
S1370
S1375
S1397
S1505
S1542
T1621
S1747
S1770
S1783
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation CCRCC S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation COAD S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation GBM S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation HNSCC S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation LSCC S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation LUAD S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation OV S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation PDAC S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation UCEC S38 S117 S135 S496 S500 T507 S509 S536 S604 T1050 S1051 S1183 S1184 S1207 S1214 S1370 S1375 S1397 S1505 S1542 T1621 S1747 S1770 S1783 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S38
S117
S135
S496
S500
T507
S509
S536
S604
T1050
S1051
S1183
S1184
S1207
S1214
S1370
S1375
S1397
S1505
S1542
T1621
S1747
S1770
S1783
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S38
S117
S135
S496
S500
T507
S509
S536
S604
T1050
S1051
S1183
S1184
S1207
S1214
S1370
S1375
S1397
S1505
S1542
T1621
S1747
S1770
S1783
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.