NDRG2: NDRG family member 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2xmq chain A
2xmq chain B
2xmq chain C
2xmr chain A
2xmr chain B
2xmr chain C
2xms chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T20 KPLLPGQT PEAAKEA 7 880 - - 82 60 - - 99 - 101 60 98 90 50 49 - - 59 27 89 16 Y47 THSVETPY GSVTFTV 1 18 - - - - - - 18 - - - - - - - - - - - - - Y55 GSVTFTVY GTPKPKR 1 45 - - - - - - 45 - - - - - - - - - - - - - T57 VTFTVYGT PKPKRPA 1 63 - - - - - - 63 - - - - - - - - - - - - - Y316 YFLQGMGY MASSCMT 3 28 - - - - - - - - 7 3 5 4 4 5 - - - - - - S319 QGMGYMAS SCMTRLS 1 8 - - - - - - - - - - - - 4 4 - - - - - - S320 GMGYMASS CMTRLSR 2 17 - - - - - - 8 - 6 3 - - - - - - - - - - T323 YMASSCMT RLSRSRT 4 53 - - 9 8 - - 8 - 12 6 5 5 - - - - - - - - S326 SSCMTRLS RSRTASL 6 564 - - 15 15 - - 99 - 78 49 58 53 98 88 - - 8 3 - - S328 CMTRLSRS RTASLTS 9 491 - - 8 6 62 72 26 - 49 29 5 5 79 72 21 5 25 12 10 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T20 KPLLPGQT PEAAKEA -1.5e-41 - -4.3e-15 - - -4.1e-19 -2e-17 -6.4e-9 - -2.2e-7 1.4e-3 Y47 THSVETPY GSVTFTV - - - - - - - - - - - Y55 GSVTFTVY GTPKPKR - - - - - - - - - - - T57 VTFTVYGT PKPKRPA - - - - - - - - - - - Y316 YFLQGMGY MASSCMT - - - - - - - - - - - S319 QGMGYMAS SCMTRLS - - - - - - - - - - - S320 GMGYMASS CMTRLSR - - - - - - - - - - - T323 YMASSCMT RLSRSRT - - - - - - - - - - - S326 SSCMTRLS RSRTASL -3.9e-58 - - - - -2.1e-16 -8.9e-18 -2.4e-28 - - - S328 CMTRLSRS RTASLTS -2.8e-22 - - -2.5e-7 - -6.4e-4 - -6.9e-21 - -0.14 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T20
Y47
Y55
T57
Y316
S319
S320
T323
S326
S328
T330
S332
T334
S335
S338
S344
S346
T348
S350
S352
S353
S355
T357
S359
S360
T366
S370
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation CCRCC T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation COAD T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation GBM T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation HNSCC T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation LSCC T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation LUAD T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation OV T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation PDAC T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation UCEC T20 Y47 Y55 T57 Y316 S319 S320 T323 S326 S328 T330 S332 T334 S335 S338 S344 S346 T348 S350 S352 S353 S355 T357 S359 S360 T366 S370 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T20
Y47
Y55
T57
Y316
S319
S320
T323
S326
S328
T330
S332
T334
S335
S338
S344
S346
T348
S350
S352
S353
S355
T357
S359
S360
T366
S370
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T20
Y47
Y55
T57
Y316
S319
S320
T323
S326
S328
T330
S332
T334
S335
S338
S344
S346
T348
S350
S352
S353
S355
T357
S359
S360
T366
S370
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.