TLE3: TLE family member 3, transcriptional corepressor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S197 DHRERESS ANNSVSP 1 8 8 - - - - - - - - - - - - - - - - - - - S201 RESSANNS VSPSESL 7 212 72 - - - - - 9 - 7 2 25 24 19 16 7 2 - - 22 7 S203 SSANNSVS PSESLRA 9 1296 114 - 98 76 - - 90 - 108 62 108 99 91 86 83 19 105 44 95 18 S205 ANNSVSPS ESLRASE 7 126 24 - 13 12 - - - - 25 17 5 5 8 8 - - 2 1 6 - S207 NSVSPSES LRASEKH 8 197 8 - 4 4 - - 44 - 7 3 10 9 4 4 - - 10 4 68 18 S211 PSESLRAS EKHRGSA 1 17 - - - - - - - - - - - - - - - - - - 15 2 S217 ASEKHRGS ADYSMEA 7 490 45 - - - - - 99 - 29 17 14 13 - - 71 15 56 24 89 18 S221 HRGSADYS MEAKKRK 2 16 8 - 4 4 - - - - - - - - - - - - - - - - S234 RKAEEKDS LSRYDSD 1 9 - - - - - - 9 - - - - - - - - - - - - - S236 AEEKDSLS RYDSDGD 1 18 - - - - - - 18 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S197 DHRERESS ANNSVSP - - - - - - - - - - - S201 RESSANNS VSPSESL 5.8e-5 - - - - - 5.8e-5 - - - - S203 SSANNSVS PSESLRA 8.7e-64 - 4.3e-17 - - 4.5e-3 1.9e-33 1.6e-22 0.056 1.4e-13 0.025 S205 ANNSVSPS ESLRASE -0.86 - - - - -0.86 - - - - - S207 NSVSPSES LRASEKH -0.42 - - - - - - - - - -0.42 S211 PSESLRAS EKHRGSA - - - - - - - - - - - S217 ASEKHRGS ADYSMEA 4.6e-5 - - - - 0.32 - - 0.072 4.6e-4 0.064 S221 HRGSADYS MEAKKRK - - - - - - - - - - - S234 RKAEEKDS LSRYDSD - - - - - - - - - - - S236 AEEKDSLS RYDSDGD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S197
S201
S203
S205
S207
S211
S217
S221
S234
S236
S240
S245
S253
T259
S263
S267
S286
S289
S292
S293
S295
T296
S311
T312
T319
T321
T328
S332
T333
T334
S355
S521
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation CCRCC S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation COAD S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation GBM S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation HNSCC S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation LSCC S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation LUAD S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation OV S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation PDAC S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation UCEC S197 S201 S203 S205 S207 S211 S217 S221 S234 S236 S240 S245 S253 T259 S263 S267 S286 S289 S292 S293 S295 T296 S311 T312 T319 T321 T328 S332 T333 T334 S355 S521 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S197
S201
S203
S205
S207
S211
S217
S221
S234
S236
S240
S245
S253
T259
S263
S267
S286
S289
S292
S293
S295
T296
S311
T312
T319
T321
T328
S332
T333
T334
S355
S521
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S197
S201
S203
S205
S207
S211
S217
S221
S234
S236
S240
S245
S253
T259
S263
S267
S286
S289
S292
S293
S295
T296
S311
T312
T319
T321
T328
S332
T333
T334
S355
S521
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.