Protein: ENSP00000453785
Gene: SNX1

LinkedOmicsKB © 2022-2023 Zhang Lab

SNX1:
sorting nexin 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S25FPGLEPESEGAAGGS930631-634933307-211310998--63122
S32SEGAAGGSEPEAGDS82458-161319179-43252019----189254
S39SEPEAGDSDTEGEDI980326-6159859487-744224211717--71297818
T41PEAGDSDTEGEDIFT741217-97919654-----1817--328414
T48TEGEDIFTGAAVVSK224----4317-------------
S64QSPKITTSLLPINNG72329-44----53997064--84394
S72LLPINNGSKENGIHE81245113-10380--99-1086210899110101--105449518
S115VLAKTLISLPPQEAT110--------73----------
S172YKVTTQTSLPLFRSK3298-96--------------6-
S188FAVKRRFSDFLGLYE91418104-10380939599-1086210899110101--105448918
Showing 1 to 10 of 15 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S25FPGLEPESEGAAGGS-2.2e-16--5.3e-12-1.4e-3--3.6e-5-----
S32SEGAAGGSEPEAGDS-9.7e-3-----1.4e-105.7e-3----
S39SEPEAGDSDTEGEDI-5.6e-9--7.9e-15-0.02--3.9e-11-0.92--0.0320.7
T41PEAGDSDTEGEDIFT-1.8e-11---1.2e-8-------1.4e-4
T48TEGEDIFTGAAVVSK-----------
S64QSPKITTSLLPINNG-0.83-------0.83---
S72LLPINNGSKENGIHE-1.1e-14--0.085---4.7e-21-0.0560.03--0.04-2.1e-9
S115VLAKTLISLPPQEAT-----------
S172YKVTTQTSLPLFRSK-----------
S188FAVKRRFSDFLGLYE-5.3e-17-0.73-7.8e-15-0.32-3e-17-2.4e-5--1.6e-30.93
Showing 1 to 10 of 15 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationCCRCCS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationCOADS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationGBMS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationHNSCCS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationLSCCS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationLUADS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationOVS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationPDACS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylationUCECS25S32S39T41T48S64S72S115S172S188S215T220S229S230S280proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.