Protein: ENSP00000459799
Gene: TNK1

LinkedOmicsKB © 2022-2023 Zhang Lab

TNK1:
tyrosine kinase non receptor 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S60RPAQRRLSEALKRLR229--------127--------10-
S94HKEPTLPSDSPRHLP19----------54--------
S96EPTLPSDSPRHLPEP514816-------17925241412----283
S468RGDQHPGSIDGDRKK865441-40292933--583388808071326--322
S502RMKGISRSLESVLSL10109538-2624971009-1086288828072691578349518
S505GISRSLESVLSLGPR224----54------------132
T514LSLGPRPTGGGSSPP3186-----------44----4-
S518PRPTGGGSSPPEIRQ3306-----------44----142
S519RPTGGGSSPPEIRQA10116597-846178669-10259108998881681658225415
S543LPPRPPLSSSSPQPS2247-134----------------
Showing 1 to 10 of 15 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S60RPAQRRLSEALKRLR-----------
S94HKEPTLPSDSPRHLP-----------
S96EPTLPSDSPRHLPEP2.8e-4-----2.8e-4----
S468RGDQHPGSIDGDRKK7.2e-33-8.8e-10-0.49-1.3e-45.3e-201.2e-16---
S502RMKGISRSLESVLSL2.4e-6-2.3e-5-0.11--0.512.7e-123.6e-3-0.98-5.6e-53.1e-8
S505GISRSLESVLSLGPR-----------
T514LSLGPRPTGGGSSPP-----------
S518PRPTGGGSSPPEIRQ-----------
S519RPTGGGSSPPEIRQA2.8e-13--8.9e-200.015-3.5e-83e-153.9e-6-0.843.3e-45e-7
S543LPPRPPLSSSSPQPS-----------
Showing 1 to 10 of 15 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationCCRCCS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationCOADS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationGBMS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationHNSCCS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationLSCCS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationLUADS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationOVS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationPDACS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylationUCECS60S94S96S468S502S505T514S518S519S543S544S545S546S587Y651proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.