- PRKAR1A:
- protein kinase cAMP-dependent type I regulatory subunit alpha
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S14 | AASEEARSLRECELY | 8 | 580 | 31 | - | 37 | 27 | - | - | 18 | - | 59 | 33 | 35 | 33 | 90 | 81 | - | - | 68 | 26 | 30 | 12 |
T75 | LQKAGTRTDSREDEI | 1 | 10 | - | - | - | - | - | - | - | - | 6 | 4 | - | - | - | - | - | - | - | - | - | - |
S77 | KAGTRTDSREDEISP | 10 | 549 | 35 | - | 36 | 27 | 48 | 51 | 71 | - | 7 | 3 | 39 | 38 | 21 | 21 | 35 | 7 | 17 | 7 | 72 | 14 |
S83 | DSREDEISPPPPNPV | 10 | 1553 | 122 | - | 103 | 80 | 97 | 100 | 99 | - | 108 | 62 | 108 | 99 | 110 | 101 | 83 | 19 | 105 | 44 | 95 | 18 |
S101 | RRRRGAISAEVYTEE | 7 | 168 | 26 | - | - | - | 2 | 7 | 26 | - | 11 | 7 | 20 | 20 | 9 | 7 | 26 | 7 | - | - | - | - |
S380 | YNSFVSLSV______ | 1 | 20 | - | - | - | - | - | - | - | - | - | - | 10 | 10 | - | - | - | - | - | - | - | - |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S14 | AASEEARSLRECELY | -7.3e-7 | - | 0.69 | - | - | -0.34 | -1.5e-5 | -8.4e-12 | - | 0.19 | -0.082 |
T75 | LQKAGTRTDSREDEI | - | - | - | - | - | - | - | - | - | - | - |
S77 | KAGTRTDSREDEISP | -5.2e-9 | - | -2.6e-3 | -1.6e-11 | - | - | -5.8e-3 | -0.92 | - | - | -0.65 |
S83 | DSREDEISPPPPNPV | -5.5e-15 | - | 3.3e-6 | -1.6e-19 | - | -4.8e-11 | -1.4e-5 | -3.6e-12 | -0.097 | 1.1e-7 | -4.7e-4 |
S101 | RRRRGAISAEVYTEE | -0.38 | - | - | - | - | - | -0.38 | - | - | - | - |
S380 | YNSFVSLSV______ | - | - | - | - | - | - | - | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |