NBR1: NBR1 autophagy cargo receptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1wj6 chain A
2bkf chain A
2cp8 chain A
2g4s chain A
2l8j chain B
2mgw chain A
2mj5 chain B
4ole chain A
4ole chain B
4ole chain C
4ole chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S57 DEENEEVS INSQGEY 2 26 - - 8 8 - - - - - - 5 5 - - - - - - - - S60 NEEVSINS QGEYEEA 2 17 - - 4 4 - - - - - - - - 5 4 - - - - - - S116 KPLAHYSS LVRVLGS 2 31 14 - - - - - 17 - - - - - - - - - - - - - T127 VLGSDMKT PEDPAVQ 1 6 - - 3 3 - - - - - - - - - - - - - - - - S135 PEDPAVQS FPLVPCD 2 34 - - 12 4 - - - - - - - - 10 8 - - - - - - S276 PFCHSKYS TPRLPAA 1 8 - - 4 4 - - - - - - - - - - - - - - - - S334 RKIHLWNS IHGLQSP 2 25 16 - - - - - 9 - - - - - - - - - - - - - S340 NSIHGLQS PKSPLGR 1 6 - - 3 3 - - - - - - - - - - - - - - - - S483 IIVDPFPS EESPDNI 4 34 - - 4 3 - - - - 5 4 5 5 4 4 - - - - - - S486 DPFPSEES PDNIEKG 3 29 - - - - 6 3 10 - 6 4 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S57 DEENEEVS INSQGEY - - - - - - - - - - - S60 NEEVSINS QGEYEEA - - - - - - - - - - - S116 KPLAHYSS LVRVLGS - - - - - - - - - - - T127 VLGSDMKT PEDPAVQ - - - - - - - - - - - S135 PEDPAVQS FPLVPCD - - - - - - - - - - - S276 PFCHSKYS TPRLPAA - - - - - - - - - - - S334 RKIHLWNS IHGLQSP - - - - - - - - - - - S340 NSIHGLQS PKSPLGR - - - - - - - - - - - S483 IIVDPFPS EESPDNI - - - - - - - - - - - S486 DPFPSEES PDNIEKG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S57
S60
S116
T127
S135
S276
S334
S340
S483
S486
T581
T586
S590
S596
S622
S625
S635
S644
T646
S656
S673
S794
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation CCRCC S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation COAD S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation GBM S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation HNSCC S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation LSCC S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation LUAD S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation OV S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation PDAC S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation UCEC S57 S60 S116 T127 S135 S276 S334 S340 S483 S486 T581 T586 S590 S596 S622 S625 S635 S644 T646 S656 S673 S794 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S57
S60
S116
T127
S135
S276
S334
S340
S483
S486
T581
T586
S590
S596
S622
S625
S635
S644
T646
S656
S673
S794
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S57
S60
S116
T127
S135
S276
S334
S340
S483
S486
T581
T586
S590
S596
S622
S625
S635
S644
T646
S656
S673
S794
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.