Protein: ENSP00000469820
Gene: PHLDB1

LinkedOmicsKB © 2022-2023 Zhang Lab

PHLDB1:
pleckstrin homology like domain family B member 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S47PHLVSLGSGRLSTAI326--44------------8352
S51SLGSGRLSTAITLLP1081126-2724837880-50292927534842982347713
T52LGSGRLSTAITLLPL217--44--------54------
S74GSAARDISLQGPGLA110----------55--------
Y156GRAPGPPYSPVPAES71989-----72---54191649942-9
S157RAPGPPYSPVPAESE6220------45-12855--38103313429
S163YSPVPAESESLVNGN18--------------71----
S165PVPAESESLVNGNHT215--------------62--7-
T172SLVNGNHTPQTATRG386------35-------81--357
S181QTATRGPSACASHSS116--------------142----
Showing 1 to 10 of 93 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S47PHLVSLGSGRLSTAI-----------
S51SLGSGRLSTAITLLP-1.9e-28--0.023-1.8e-15--4.6e-8-3.5e-7-8.7e-7-0.21-1.4e-6
T52LGSGRLSTAITLLPL-----------
S74GSAARDISLQGPGLA-----------
Y156GRAPGPPYSPVPAES-----------
S157RAPGPPYSPVPAESE-0.32--------0.72-0.3-
S163YSPVPAESESLVNGN-----------
S165PVPAESESLVNGNHT-----------
T172SLVNGNHTPQTATRG-----------
S181QTATRGPSACASHSS-----------
Showing 1 to 10 of 93 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationCCRCCS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationCOADS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationGBMS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationHNSCCS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationLSCCS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationLUADS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationOVS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationPDACS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylationUCECS47S51T52S74Y156S157S163S165T172S181S185S187S188S191S192S203S220S223S289S291Y292S310S314S324S334S377S381S404S419S421S430S443S453S461S463S465S470T476T477S489S501S506T516S518S520T522S526S533S535S539Y542S543S546T548S551S555S563S564S578T580S583S638S654S661S664S665S678S682S692S693T694S696T697S817S876S896S946T970S971S978S983S987S988S989S990S992S1002S1004S1007T1015S1017S1198T1223proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.