Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y22 AAYHLHIY PQLSTTE 1 8 - - 4 4 - - - - - - - - - - - - - - - - S26 LHIYPQLS TTESQAS 7 244 - - 24 23 - - 17 - 12 8 15 12 50 48 - - 13 5 8 9 S716 AEKAAGMS SPGAQSH 4 52 7 - - - - - - - 11 7 - - 5 4 15 3 - - - - S717 EKAAGMSS PGAQSHP 10 967 104 - 33 24 31 40 99 - 67 40 74 67 95 89 76 18 28 13 53 16 S732 EELPRGAS TPSEKLY 1 35 - - - - - - 35 - - - - - - - - - - - - - T733 ELPRGAST PSEKLYR 2 31 - - - - - - - - - - 9 8 - - - - - - 11 3 S1027 LYRHQKQS IIRLQSL 1 7 7 - - - - - - - - - - - - - - - - - - - S1043 RGHLQRKS FSQMISE 10 1039 56 - 13 12 44 54 99 - 102 59 89 81 40 37 83 19 100 43 90 18 S1045 HLQRKSFS QMISEKQ 2 26 - - - - - - 17 - - - - - - - - - - - 7 2 S1099 EDGGHLAS EPEVQPS 3 41 - - - - - - - - - - 9 7 9 8 - - - - 6 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y22 AAYHLHIY PQLSTTE - - - - - - - - - - - S26 LHIYPQLS TTESQAS 0.19 - -0.53 - - - - 0.013 - - - S716 AEKAAGMS SPGAQSH - - - - - - - - - - - S717 EKAAGMSS PGAQSHP 3.4e-4 - 1.9e-7 0.9 - 0.018 0.39 0.011 0.39 -0.096 -0.87 S732 EELPRGAS TPSEKLY - - - - - - - - - - - T733 ELPRGAST PSEKLYR - - - - - - - - - - - S1027 LYRHQKQS IIRLQSL - - - - - - - - - - - S1043 RGHLQRKS FSQMISE 5.3e-8 - - -0.83 - 2.7e-21 0.49 6.9e-6 0.33 0.016 -6.0e-4 S1045 HLQRKSFS QMISEKQ - - - - - - - - - - - S1099 EDGGHLAS EPEVQPS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y22
S26
S716
S717
S732
T733
S1027
S1043
S1045
S1099
S1109
S1114
S1115
S1122
S1168
S1179
S1197
S1242
T1252
S1253
S1261
S1267
T1271
S1281
S1290
T1295
S1308
S1323
S1325
S1329
S1331
T1346
T1348
T1353
S1354
S1356
T1357
S1382
S1398
S1405
S1408
S1430
S1682
Y1928
S1935
S1992
S1999
T2001
S2002
S2004
T2005
S2007
T2033
S2035
S2049
S2050
Y2140
S2141
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation CCRCC Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation COAD Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation GBM Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation HNSCC Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation LSCC Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation LUAD Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation OV Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation PDAC Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation UCEC Y22 S26 S716 S717 S732 T733 S1027 S1043 S1045 S1099 S1109 S1114 S1115 S1122 S1168 S1179 S1197 S1242 T1252 S1253 S1261 S1267 T1271 S1281 S1290 T1295 S1308 S1323 S1325 S1329 S1331 T1346 T1348 T1353 S1354 S1356 T1357 S1382 S1398 S1405 S1408 S1430 S1682 Y1928 S1935 S1992 S1999 T2001 S2002 S2004 T2005 S2007 T2033 S2035 S2049 S2050 Y2140 S2141 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
Y22
S26
S716
S717
S732
T733
S1027
S1043
S1045
S1099
S1109
S1114
S1115
S1122
S1168
S1179
S1197
S1242
T1252
S1253
S1261
S1267
T1271
S1281
S1290
T1295
S1308
S1323
S1325
S1329
S1331
T1346
T1348
T1353
S1354
S1356
T1357
S1382
S1398
S1405
S1408
S1430
S1682
Y1928
S1935
S1992
S1999
T2001
S2002
S2004
T2005
S2007
T2033
S2035
S2049
S2050
Y2140
S2141
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
Y22
S26
S716
S717
S732
T733
S1027
S1043
S1045
S1099
S1109
S1114
S1115
S1122
S1168
S1179
S1197
S1242
T1252
S1253
S1261
S1267
T1271
S1281
S1290
T1295
S1308
S1323
S1325
S1329
S1331
T1346
T1348
T1353
S1354
S1356
T1357
S1382
S1398
S1405
S1408
S1430
S1682
Y1928
S1935
S1992
S1999
T2001
S2002
S2004
T2005
S2007
T2033
S2035
S2049
S2050
Y2140
S2141
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.