Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2wx3 chain A
2wx3 chain B
2wx3 chain C
4b6h chain A
4b6h chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S60 TLFVYRRS ASPYHGF 1 10 - - - - - - - - 7 3 - - - - - - - - - - S62 FVYRRSAS PYHGFTI 3 219 - - - - - - 90 - - - - - - - - - 26 11 83 9 Y64 YRRSASPY HGFTIVN 1 9 - - 5 4 - - - - - - - - - - - - - - - - S142 QAARDKQS PSQANGC 4 111 - - - - - - 72 - 5 3 - - - - - - 7 3 18 3 S144 ARDKQSPS QANGCSD 6 455 - - 12 9 - - 63 - 74 43 53 48 76 67 - - 7 3 - - S150 PSQANGCS DHRPIDI 3 51 - - 4 4 - - - - 6 4 - - 17 16 - - - - - - S179 QMGDSNIS SPGLQPS 3 36 - - - - - - - - - - - - 5 4 - - 4 1 19 3 S180 MGDSNISS PGLQPST 8 401 22 - - - 11 15 99 - 11 6 35 34 23 19 - - 17 9 82 18 S186 SSPGLQPS TQLSNLG 2 12 - - - - - - - - - - - - - - - - 4 2 6 - T187 SPGLQPST QLSNLGS 1 6 - - - - - - - - - - - - - - - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S60 TLFVYRRS ASPYHGF - - - - - - - - - - - S62 FVYRRSAS PYHGFTI 0.2 - - - - - - - - 0.2 - Y64 YRRSASPY HGFTIVN - - - - - - - - - - - S142 QAARDKQS PSQANGC - - - - - - - - - - - S144 ARDKQSPS QANGCSD -0.052 - - - - -0.021 -0.23 0.88 - - - S150 PSQANGCS DHRPIDI - - - - - - - - - - - S179 QMGDSNIS SPGLQPS - - - - - - - - - - - S180 MGDSNISS PGLQPST 0.18 - - - - - -0.47 0.41 - - 0.028 S186 SSPGLQPS TQLSNLG - - - - - - - - - - - T187 SPGLQPST QLSNLGS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S60
S62
Y64
S142
S144
S150
S179
S180
S186
T187
S190
S194
T197
T225
S226
S315
S319
T321
T328
S353
S364
S388
T401
S422
T430
S451
S453
S462
S522
S523
S525
T528
T531
S534
S539
S545
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation CCRCC S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation COAD S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation GBM S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation HNSCC S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation LSCC S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation LUAD S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation OV S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation PDAC S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation UCEC S60 S62 Y64 S142 S144 S150 S179 S180 S186 T187 S190 S194 T197 T225 S226 S315 S319 T321 T328 S353 S364 S388 T401 S422 T430 S451 S453 S462 S522 S523 S525 T528 T531 S534 S539 S545 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S60
S62
Y64
S142
S144
S150
S179
S180
S186
T187
S190
S194
T197
T225
S226
S315
S319
T321
T328
S353
S364
S388
T401
S422
T430
S451
S453
S462
S522
S523
S525
T528
T531
S534
S539
S545
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S60
S62
Y64
S142
S144
S150
S179
S180
S186
T187
S190
S194
T197
T225
S226
S315
S319
T321
T328
S353
S364
S388
T401
S422
T430
S451
S453
S462
S522
S523
S525
T528
T531
S534
S539
S545
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.