TOR1AIP1: torsin 1A interacting protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4tvs chain A
4tvs chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S39 LAPQNGGS SDAPAYR 4 48 9 - - - - - 9 - - - 5 4 - - - - - - 19 2 Y45 GSSDAPAY RTPPSRQ 1 9 - - - - - - 9 - - - - - - - - - - - - - T47 SDAPAYRT PPSRQGR 3 72 - - - - - - 46 - - - - - - - - - 4 1 16 5 S60 GRREVRFS DEPPEVY 7 158 - - 12 12 5 12 63 - - - 5 5 4 4 - - 8 2 23 3 Y67 SDEPPEVY GDFEPLV 1 17 17 - - - - - - - - - - - - - - - - - - - S79 PLVAKERS PVGKRTR 8 984 118 - - - 46 52 99 - 15 9 102 94 101 92 - - 105 43 90 18 S94 LEEFRSDS AKEEVRE 4 77 - - 4 4 - - 44 - - - 5 4 8 8 - - - - - - S135 TRLQQQHS EQPPLQP 9 1098 89 - 90 70 48 42 55 - 102 58 98 87 100 93 - - 70 30 55 11 S143 EQPPLQPS PVMTRRG 9 1409 122 - 99 76 92 87 99 - 108 62 108 99 110 101 - - 94 39 95 18 T147 LQPSPVMT RRGLRDS 1 7 7 - - - - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S39 LAPQNGGS SDAPAYR - - - - - - - - - - - Y45 GSSDAPAY RTPPSRQ - - - - - - - - - - - T47 SDAPAYRT PPSRQGR - - - - - - - - - - - S60 GRREVRFS DEPPEVY - - - - - - - - - - - Y67 SDEPPEVY GDFEPLV - - - - - - - - - - - S79 PLVAKERS PVGKRTR -7.8e-26 - - -0.24 - - -1.7e-17 -2.9e-3 - -3.5e-6 -5.5e-10 S94 LEEFRSDS AKEEVRE - - - - - - - - - - - S135 TRLQQQHS EQPPLQP 0.018 - 0.079 -0.16 - -0.19 0.38 5.5e-3 - 3.6e-3 0.5 S143 EQPPLQPS PVMTRRG 1.6e-6 - 0.051 6.1e-5 - 0.057 0.034 0.22 - 3.6e-3 -0.15 T147 LQPSPVMT RRGLRDS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S39
Y45
T47
S60
Y67
S79
S94
S135
S143
T147
S154
S156
S157
S163
S164
T166
S179
S207
S215
T220
S227
S228
S230
S231
T233
T234
S242
S245
S253
S254
Y256
S264
S266
S277
T286
S305
S315
S317
S319
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation CCRCC S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation COAD S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation GBM S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation HNSCC S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation LSCC S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation LUAD S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation OV S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation PDAC S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation UCEC S39 Y45 T47 S60 Y67 S79 S94 S135 S143 T147 S154 S156 S157 S163 S164 T166 S179 S207 S215 T220 S227 S228 S230 S231 T233 T234 S242 S245 S253 S254 Y256 S264 S266 S277 T286 S305 S315 S317 S319 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S39
Y45
T47
S60
Y67
S79
S94
S135
S143
T147
S154
S156
S157
S163
S164
T166
S179
S207
S215
T220
S227
S228
S230
S231
T233
T234
S242
S245
S253
S254
Y256
S264
S266
S277
T286
S305
S315
S317
S319
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S39
Y45
T47
S60
Y67
S79
S94
S135
S143
T147
S154
S156
S157
S163
S164
T166
S179
S207
S215
T220
S227
S228
S230
S231
T233
T234
S242
S245
S253
S254
Y256
S264
S266
S277
T286
S305
S315
S317
S319
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.