Protein: ENSP00000477213
Gene: APBB1

LinkedOmicsKB © 2022-2023 Zhang Lab

APBB1:
amyloid beta precursor protein binding family B member 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T43LNAKLQATAVGPKDL269----------------421611-
S52VGPKDLRSAMGEGGG2179---------------53--
S118KGLIHLYSELELSAH246------36---55--------
S205GPREHSKSASLLFGM10101977-7562152099-30159485102924297634839
S207REHSKSASLLFGMRN723614-98--8---39382319144--537
S293ASPSQGSSPQEESQL143------43-------------
S345TLTFPAQSLSPEPLP18--44----------------
S347TFPAQSLSPEPLPQE3122------79---------83302
S517RCLVNGLSLDHSKLV101158114-9976151299-103581049598891967129647
S699GVQSLWGSLKPKRLG72449-66474537---20171716----6-
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T43LNAKLQATAVGPKDL0.29--------0.29-
S52VGPKDLRSAMGEGGG-----------
S118KGLIHLYSELELSAH-----------
S205GPREHSKSASLLFGM0.65--5.9e-5--0.015-0.31-0.014-1.3e-9-
S207REHSKSASLLFGMRN-8.2e-7------8.9e-7-0.04---
S293ASPSQGSSPQEESQL-----------
S345TLTFPAQSLSPEPLP-----------
S347TFPAQSLSPEPLPQE-----------
S517RCLVNGLSLDHSKLV-5.4e-3-0.014--0.31-5.8e-24-1.0e-4-0.016-
S699GVQSLWGSLKPKRLG-9.7e-4--0.081----3.5e-3----
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationCCRCCT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationCOADT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationGBMT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationHNSCCT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationLSCCT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationLUADT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationOVT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationPDACT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylationUCECT43S52S118S205S207S293S345S347S517S699T709proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.