GRIN2B: glutamate ionotropic receptor NMDA type subunit 2B
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5ewj chain B
5ewj chain D
5ewl chain B
5ewl chain D
5ewm chain B
5ewm chain D
7eu8 chain B
7eu8 chain D
7kl0 chain C
7kl0 chain D
7kl1 chain C
7kl1 chain D
7kl2 chain B
7uis chain B
7ujp chain C
7ujp chain D
7ujq chain C
7ujq chain D
7ujr chain B
7ujs chain B
7ujt chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S882 VAIEERQS VMNSPTA 1 26 - - - - - - 26 - - - - - - - - - - - - - S886 ERQSVMNS PTATMNN 1 99 - - - - - - 99 - - - - - - - - - - - - - T888 QSVMNSPT ATMNNTH 1 27 - - - - - - 27 - - - - - - - - - - - - - S917 NLSGVNGS PQSALDF 1 99 - - - - - - 99 - - - - - - - - - - - - - S940 DISEHRRS FTHSDCK 1 80 - - - - - - 80 - - - - - - - - - - - - - Y1039 HSQLSDLY GKFSFKS 1 9 - - - - - - 9 - - - - - - - - - - - - - S1058 GHDDLIRS DVSDIST 1 9 - - - - - - 9 - - - - - - - - - - - - - S1061 DLIRSDVS DISTHTV 1 53 - - - - - - 53 - - - - - - - - - - - - - T1065 SDVSDIST HTVTYGN 1 18 - - - - - - 18 - - - - - - - - - - - - - T1067 VSDISTHT VTYGNIE 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S882 VAIEERQS VMNSPTA - - - - - - - - - - - S886 ERQSVMNS PTATMNN - - - - - - - - - - - T888 QSVMNSPT ATMNNTH - - - - - - - - - - - S917 NLSGVNGS PQSALDF - - - - - - - - - - - S940 DISEHRRS FTHSDCK - - - - - - - - - - - Y1039 HSQLSDLY GKFSFKS - - - - - - - - - - - S1058 GHDDLIRS DVSDIST - - - - - - - - - - - S1061 DLIRSDVS DISTHTV - - - - - - - - - - - T1065 SDVSDIST HTVTYGN - - - - - - - - - - - T1067 VSDISTHT VTYGNIE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S882
S886
T888
S917
S940
Y1039
S1058
S1061
T1065
T1067
S1088
S1116
S1143
S1255
S1259
S1284
S1303
S1479
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation CCRCC S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation COAD S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation GBM S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation HNSCC S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation LSCC S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation LUAD S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation OV S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation PDAC S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation UCEC S882 S886 T888 S917 S940 Y1039 S1058 S1061 T1065 T1067 S1088 S1116 S1143 S1255 S1259 S1284 S1303 S1479 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S882
S886
T888
S917
S940
Y1039
S1058
S1061
T1065
T1067
S1088
S1116
S1143
S1255
S1259
S1284
S1303
S1479
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S882
S886
T888
S917
S940
Y1039
S1058
S1061
T1065
T1067
S1088
S1116
S1143
S1255
S1259
S1284
S1303
S1479
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.