BIRC2: baculoviral IAP repeat containing 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1qbh chain A
2l9m chain A
3d9t chain A
3d9t chain B
3d9u chain A
3m1d chain A
3m1d chain B
3mup chain A
3mup chain B
3mup chain C
3mup chain D
3oz1 chain A
3oz1 chain B
3oz1 chain C
3oz1 chain D
3t6p chain A
3uw4 chain A
4eb9 chain A
4eb9 chain B
4eb9 chain C
4eb9 chain D
4hy4 chain A
4hy4 chain B
4hy5 chain A
4hy5 chain B
4kmn chain A
4lge chain A
4lge chain B
4lgu chain A
4lgu chain B
4mti chain A
4mti chain B
4mu7 chain A
4mu7 chain B
5m6n chain A
5m6n chain B
6exw chain A
6exw chain C
6hpr chain A
6w74 chain A
6w7o chain C
6w7o chain D
6w8i chain D
6w8i chain E
6w8i chain F
7qgj chain A
7qgj chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S98 DNWKLGDS PIQKHKQ 6 308 - - 56 37 - - 81 - - - 15 13 40 36 - - 17 7 6 - S111 KQLYPSCS FIQNLVS 1 7 - - - - - - - - - - - - - - - - 5 2 - - S118 SFIQNLVS ASLGSTS 2 18 - - - - - - - - - - 5 5 4 4 - - - - - - S120 IQNLVSAS LGSTSKN 1 17 - - - - - - - - - - - - 9 8 - - - - - - S123 LVSASLGS TSKNTSP 1 10 - - - - - - - - 6 4 - - - - - - - - - - S125 SASLGSTS KNTSPMR 2 18 - - - - - - - - 6 3 - - 5 4 - - - - - - S140 NSFAHSLS PTLEHSS 2 36 - - - - - - 9 - 18 9 - - - - - - - - - - T142 FAHSLSPT LEHSSLF 1 72 - - - - - - 72 - - - - - - - - - - - - - S170 SRAVEDIS SSRTNPY 1 6 - - - - - - - - - - - - - - - - - - 6 - S172 AVEDISSS RTNPYSY 1 6 - - - - - - - - - - - - - - - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S98 DNWKLGDS PIQKHKQ 0.002 - 6e-8 - - - - -0.29 - - - S111 KQLYPSCS FIQNLVS - - - - - - - - - - - S118 SFIQNLVS ASLGSTS - - - - - - - - - - - S120 IQNLVSAS LGSTSKN - - - - - - - - - - - S123 LVSASLGS TSKNTSP - - - - - - - - - - - S125 SASLGSTS KNTSPMR - - - - - - - - - - - S140 NSFAHSLS PTLEHSS - - - - - - - - - - - T142 FAHSLSPT LEHSSLF - - - - - - - - - - - S170 SRAVEDIS SSRTNPY - - - - - - - - - - - S172 AVEDISSS RTNPYSY - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S98
S111
S118
S120
S123
S125
S140
T142
S170
S172
S253
S260
S554
S557
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation CCRCC S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation COAD S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation GBM S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation HNSCC S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation LSCC S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation LUAD S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation OV S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation PDAC S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation UCEC S98 S111 S118 S120 S123 S125 S140 T142 S170 S172 S253 S260 S554 S557 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S98
S111
S118
S120
S123
S125
S140
T142
S170
S172
S253
S260
S554
S557
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S98
S111
S118
S120
S123
S125
S140
T142
S170
S172
S253
S260
S554
S557
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.