CASP8AP2: caspase 8 associated protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S18 TSLFDVFS ASPLKNN 1 9 - - - - - - - - - - - - 5 4 - - - - - - S20 LFDVFSAS PLKNNDE 4 41 - - - - - - - - 10 6 5 4 5 4 - - - - 5 2 S29 LKNNDEGS LDIYAGL 6 251 78 - - - - - 8 - 48 28 34 32 5 4 - - - - 11 3 S168 TKDLKSRS PHLDDCS 2 48 - - - - - - - - - - 15 15 - - 15 3 - - - - T460 AMHQWENT PLKAERH 1 7 - - - - - - - - - - - - - - - - - - 5 2 S567 KKLNLTLS PAKKQPV 10 809 87 - 12 10 30 23 18 - 96 55 103 91 33 26 67 17 20 8 95 18 S658 TNKEDENS LLVRSVD 4 199 25 - 5 4 - - - - - - 54 49 34 28 - - - - - - T793 FEPSVIVT PLVESKS 2 60 - - - - - - - - - - 5 5 - - - - - - 41 9 S800 TPLVESKS CHLEPCL 1 9 - - - - - - - - - - - - 5 4 - - - - - - S815 PKETLDSS LQQTELM 3 42 7 - - - - - - - - - - - - - 22 4 - - - 9
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S18 TSLFDVFS ASPLKNN - - - - - - - - - - - S20 LFDVFSAS PLKNNDE - - - - - - - - - - - S29 LKNNDEGS LDIYAGL 1.3e-4 - - - - 0.98 7.7e-8 - - - - S168 TKDLKSRS PHLDDCS - - - - - - - - - - - T460 AMHQWENT PLKAERH - - - - - - - - - - - S567 KKLNLTLS PAKKQPV 1.3e-43 - - 0.017 - 3.2e-15 4.7e-33 9.3e-13 0.015 - 0.035 S658 TNKEDENS LLVRSVD 6.4e-12 - - - - - 5e-16 0.11 - - - T793 FEPSVIVT PLVESKS - - - - - - - - - - - S800 TPLVESKS CHLEPCL - - - - - - - - - - - S815 PKETLDSS LQQTELM - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S18
S20
S29
S168
T460
S567
S658
T793
S800
S815
S875
S940
S942
S960
S1161
S1187
S1253
S1260
T1261
T1277
S1278
S1321
S1326
S1327
T1340
S1353
S1364
S1368
S1380
S1383
S1537
T1552
S1554
S1601
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation CCRCC S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation COAD S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation GBM S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation HNSCC S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation LSCC S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation LUAD S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation OV S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation PDAC S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation UCEC S18 S20 S29 S168 T460 S567 S658 T793 S800 S815 S875 S940 S942 S960 S1161 S1187 S1253 S1260 T1261 T1277 S1278 S1321 S1326 S1327 T1340 S1353 S1364 S1368 S1380 S1383 S1537 T1552 S1554 S1601 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S18
S20
S29
S168
T460
S567
S658
T793
S800
S815
S875
S940
S942
S960
S1161
S1187
S1253
S1260
T1261
T1277
S1278
S1321
S1326
S1327
T1340
S1353
S1364
S1368
S1380
S1383
S1537
T1552
S1554
S1601
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S18
S20
S29
S168
T460
S567
S658
T793
S800
S815
S875
S940
S942
S960
S1161
S1187
S1253
S1260
T1261
T1277
S1278
S1321
S1326
S1327
T1340
S1353
S1364
S1368
S1380
S1383
S1537
T1552
S1554
S1601
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.