CLIP1: CAP-Gly domain containing linker protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2cp5 chain A
2cp6 chain A
2e3h chain A
2e3i chain A
2e4h chain A
2hqh chain E
2hqh chain F
2hqh chain G
2hqh chain H
2qk0 chain A
3e2u chain E
3e2u chain F
3e2u chain G
3e2u chain H
3rdv chain A
3rdv chain B
3rdv chain C
3rdv chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T25 PGSTALKT PTAVVAP 9 925 8 - 83 70 4 5 82 - 68 42 63 59 97 88 - - 100 43 95 18 S44 ISSEKASS TPSSETQ 2 71 - - - - - - - - 23 12 - - - - - - - - 29 7 T45 SSEKASST PSSETQE 2 14 - - 4 4 - - - - - - - - - - - - - - 6 - S47 EKASSTPS SETQEEF 3 117 - - 4 4 - - - - 57 31 - - - - - - - - 12 9 S48 KASSTPSS ETQEEFV 5 154 - - 4 4 - - 9 - 68 38 - - 8 7 - - - - 14 2 T50 SSTPSSET QEEFVDD 2 45 8 - - - - - - - 24 13 - - - - - - - - - - T139 DEANGLQT TPASRAT 1 9 - - - - 4 5 - - - - - - - - - - - - - - T140 EANGLQTT PASRATS 4 34 - - 4 4 - - - - 5 4 5 4 - - - - - - 5 3 S143 GLQTTPAS RATSPLC 10 740 57 - 12 11 43 55 71 - 45 28 34 31 27 25 62 15 88 36 85 15 T146 TTPASRAT SPLCTST 2 15 - - - - - - 9 - - - - - - - - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T25 PGSTALKT PTAVVAP -0.49 - 0.09 - - -2.3e-4 0.057 0.039 - -3.3e-7 1.5e-6 S44 ISSEKASS TPSSETQ -0.57 - - - - -0.57 - - - - - T45 SSEKASST PSSETQE - - - - - - - - - - - S47 EKASSTPS SETQEEF 0.051 - - - - 0.051 - - - - - S48 KASSTPSS ETQEEFV 0.13 - - - - 0.13 - - - - - T50 SSTPSSET QEEFVDD 0.13 - - - - 0.13 - - - - - T139 DEANGLQT TPASRAT - - - - - - - - - - - T140 EANGLQTT PASRATS - - - - - - - - - - - S143 GLQTTPAS RATSPLC 1.1e-3 - - 0.15 - -0.85 1.7e-5 5.3e-3 -0.61 -7.8e-5 2.2e-6 T146 TTPASRAT SPLCTST - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T25
S44
T45
S47
S48
T50
T139
T140
S143
T146
S147
T151
S155
S158
S159
S160
S162
T163
T182
S193
S195
S197
S200
S204
T286
T287
S304
S306
S310
S312
S314
S315
S318
S341
S510
T562
T564
S978
S1009
S1108
S1236
S1302
S1303
S1304
S1305
T1308
T1310
S1321
S1328
S1348
Y1362
S1364
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation CCRCC T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation COAD T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation GBM T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation HNSCC T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation LSCC T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation LUAD T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation OV T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation PDAC T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation UCEC T25 S44 T45 S47 S48 T50 T139 T140 S143 T146 S147 T151 S155 S158 S159 S160 S162 T163 T182 S193 S195 S197 S200 S204 T286 T287 S304 S306 S310 S312 S314 S315 S318 S341 S510 T562 T564 S978 S1009 S1108 S1236 S1302 S1303 S1304 S1305 T1308 T1310 S1321 S1328 S1348 Y1362 S1364 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T25
S44
T45
S47
S48
T50
T139
T140
S143
T146
S147
T151
S155
S158
S159
S160
S162
T163
T182
S193
S195
S197
S200
S204
T286
T287
S304
S306
S310
S312
S314
S315
S318
S341
S510
T562
T564
S978
S1009
S1108
S1236
S1302
S1303
S1304
S1305
T1308
T1310
S1321
S1328
S1348
Y1362
S1364
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T25
S44
T45
S47
S48
T50
T139
T140
S143
T146
S147
T151
S155
S158
S159
S160
S162
T163
T182
S193
S195
S197
S200
S204
T286
T287
S304
S306
S310
S312
S314
S315
S318
S341
S510
T562
T564
S978
S1009
S1108
S1236
S1302
S1303
S1304
S1305
T1308
T1310
S1321
S1328
S1348
Y1362
S1364
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.