TNFAIP3: TNF alpha induced protein 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2eqe chain A
2eqf chain A
2eqg chain A
2vfj chain A
2vfj chain B
2vfj chain C
2vfj chain D
3dkb chain A
3dkb chain B
3dkb chain C
3dkb chain D
3dkb chain E
3dkb chain F
3oj3 chain I
3oj3 chain J
3oj3 chain K
3oj3 chain L
3oj3 chain M
3oj3 chain N
3oj3 chain O
3oj3 chain P
3oj4 chain C
3oj4 chain F
3vuw chain E
3vuw chain F
3vuw chain G
3vux chain E
3vux chain F
3vux chain G
3vuy chain D
3vuy chain E
3vuy chain F
3zjd chain A
3zjd chain B
3zje chain A
3zje chain B
3zjf chain A
3zjf chain B
3zjg chain A
3zjg chain B
5lrx chain A
5lrx chain C
5lrx chain E
5lrx chain F
5v3b chain A
5v3b chain B
5v3b chain C
5v3b chain D
5v3b chain E
5v3b chain F
5v3p chain A
5v3p chain B
5v3p chain C
5v3p chain D
5v3p chain E
5v3p chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S220 KMLRSLES GSNFAPL 6 137 7 - - - - - 9 - 25 14 25 23 4 5 21 4 - - - - S222 LRSLESGS NFAPLKV 3 36 9 - - - - - - - - - 10 9 - - - - - - 6 2 S376 AQNPMEPS VPQLSLM 3 53 - - - - 5 4 - - 24 12 - - - - 6 2 - - - - S381 EPSVPQLS LMDVKCE 8 339 - - - - 28 35 9 - 52 31 39 36 13 13 12 4 26 11 24 6 S423 NKLPKLNS KPGPEGL 3 43 16 - - - - - - - - - 5 5 - - 13 4 - - - - S453 LAWNPEES TGGPHSA 2 13 7 - - - - - - - - - - - - - - - 5 1 - - T454 AWNPEEST GGPHSAP 1 8 - - 4 4 - - - - - - - - - - - - - - - - S459 ESTGGPHS APPTAPS 10 948 48 - 80 60 33 21 61 - 108 62 94 85 80 72 7 1 84 35 5 12 T463 GPHSAPPT APSPFLF 6 130 9 - 18 8 - - - - 41 22 5 4 9 8 - - 5 1 - - S466 SAPPTAPS PFLFSET 2 50 - - 4 4 - - - - 27 15 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S220 KMLRSLES GSNFAPL 0.42 - - - - 6.8e-4 -0.024 - - - - S222 LRSLESGS NFAPLKV - - - - - - - - - - - S376 AQNPMEPS VPQLSLM -0.27 - - - - -0.27 - - - - - S381 EPSVPQLS LMDVKCE 0.022 - - 0.093 - 1.1e-6 -4.1e-3 - - 0.37 - S423 NKLPKLNS KPGPEGL - - - - - - - - - - - S453 LAWNPEES TGGPHSA - - - - - - - - - - - T454 AWNPEEST GGPHSAP - - - - - - - - - - - S459 ESTGGPHS APPTAPS 2.6e-28 - 8.5e-19 1.5e-3 - 6.9e-14 6.3e-3 -0.23 - 2.1e-9 - T463 GPHSAPPT APSPFLF 0.64 - - - - 0.64 - - - - - S466 SAPPTAPS PFLFSET 8.9e-3 - - - - 8.9e-3 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S220
S222
S376
S381
S423
S453
T454
S459
T463
S466
S471
S537
T553
S573
S575
S578
S592
T625
S641
S645
T647
S698
S729
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation CCRCC S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation COAD S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation GBM S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation HNSCC S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation LSCC S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation LUAD S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation OV S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation PDAC S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation UCEC S220 S222 S376 S381 S423 S453 T454 S459 T463 S466 S471 S537 T553 S573 S575 S578 S592 T625 S641 S645 T647 S698 S729 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S220
S222
S376
S381
S423
S453
T454
S459
T463
S466
S471
S537
T553
S573
S575
S578
S592
T625
S641
S645
T647
S698
S729
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S220
S222
S376
S381
S423
S453
T454
S459
T463
S466
S471
S537
T553
S573
S575
S578
S592
T625
S641
S645
T647
S698
S729
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.